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LAMP1 / CD107a Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249421

LAMP1 Antibody, CD107a Antibody, CD107a antigen Antibody, LAMP-1 Antibody, LGP120 Antibody, LAMPA Antibody Description: LAMP1, also known as CD107a, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate… More details

$650 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LAMP1 / CD107a, Monoclonal Antibody
Full Product Name
Anti-LAMP1 / CD107a Antibody (clone 5H6) IHC-plus
Product Gene Name
anti-LAMP1 / CD107a antibody
Product Synonym Names
Mouse Monoclonal [clone 5H6] (IgG1) to Human LAMP1 / CD107a; Human LAMP1 / CD107a; CD107a antigen; LAMP-1; LGP120; LAMPA
Clonality
Monoclonal
Isotype
IgG1
Clone Number
5H6
Host
Mouse
Species Reactivity
Mouse, Bovine, Rat, Pig, Human
Form/Format
PBS, 10 mM sodium azide.
Purity/Purification
Affinity purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Molecular Weight
38,986 Da
OMIM
153330
3D Structure
ModBase 3D Structure for P11279
Target Species
Human
Applications Tested/Suitable for anti-LAMP1 / CD107a antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-LAMP1 / CD107a antibody
IF (1:2000)
IHC-P (10 ug/ml)
WB (1:10000)

Immunohistochemistry (IHC) of anti-LAMP1 / CD107a antibody

Anti-LAMP1 / CD107a antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Mouse Anti-LAMP1 / CD107a Monoclonal Antibody – Cat# MBS249421

Immunohistochemistry (IHC) of anti-LAMP1 / CD107a antibody

Anti-LAMP1 / CD107a antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Mouse Anti-LAMP1 / CD107a Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249421

Immunocytochemistry (ICC) of anti-LAMP1 / CD107a antibody

HeLa cells staining with CD107a / LAMP1 antibody (red), and counterstained with chicken polyclonal antibody to Vimentin (green) and DNA (blue). The CD107a / LAMP1 antibody antibody reveals strong punctate cytoplasmic staining corresponding to lysosomes and late endosomes, while the Vimentin antibody reveals cytoplasmic intermediate filaments.
Mouse Anti-LAMP1 / CD107a Monoclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS249421

Western Blot (WB) of anti-LAMP1 / CD107a antibody

Western strip blots of HeLa cell crude extracts stained with anti LAMP1 antibody CD107a / LAMP1 antibody in strip 9. Lane 10 shows staining another LAMP1 antibody. Both antibodies bind to a diffuse band running at between ~90 and ~120kDa as expected, and show no appreciably cross reactivity with any other protein.
Mouse Anti-LAMP1 / CD107a Monoclonal Antibody, Western Blot (WB) – Cat# MBS249421

Other Notes

Small volumes of anti-LAMP1 / CD107a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LAMP1 / CD107a purchase

MBS249421 is an antibody targeting LAMP1 / CD107a. Also known as Anti-LAMP1 / CD107a Antibody (clone 5H6) IHC-plus. Reactive in Mouse, Bovine, Rat, Pig, Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LAMP1 / CD107a. It may not necessarily be applicable to this product.

NCBI GI #
112380628
NCBI GeneID
3916
NCBI Accession #
NP_005552.3
UniProt Primary Accession #
P11279
UniProt Secondary Accession #
Q8WU33; Q96I40; Q9BRD2; Q9NP13; B4DWL3
UniProt Related Accession #
P11279
GenBank Nucleotide #
NM_005561.3
NCBI Official Full Name
lysosome-associated membrane glycoprotein 1
NCBI Official Synonym Full Names
lysosomal associated membrane protein 1
NCBI Official Symbol
LAMP1
NCBI Official Synonym Symbols
LAMPA; CD107a; LGP120
UniProt Protein Name
Lysosome-associated membrane glycoprotein 1
UniProt Synonym Protein Names
CD107 antigen-like family member A; CD_antigen: CD107a
UniProt Gene Name
LAMP1
UniProt Synonym Gene Names
LAMP-1; Lysosome-associated membrane protein 1
UniProt Entry Name
LAMP1_HUMAN
NCBI Protein Information
lysosome-associated membrane glycoprotein 1

NCBI Summary for LAMP1 / CD107a

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]

UniProt Comments for LAMP1 / CD107a

LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q34

Cellular Component: cell soma; cytoplasm; dendrite; endosome membrane; external side of plasma membrane; integral to plasma membrane; late endosome; lysosomal membrane; lysosome; melanosome; membrane; multivesicular body; perinuclear region of cytoplasm; plasma membrane; sarcolemma; synaptic vesicle

Molecular Function: enzyme binding; protein binding; protein domain specific binding; viral receptor activity

Biological Process: autophagic cell death; autophagy; entry of virus into host cell; induction of apoptosis by granzyme; positive regulation of natural killer cell degranulation; positive regulation of natural killer cell mediated cytotoxicity; protein stabilization
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Research Articles on LAMP1 / CD107a

1. A unique triad of histidines of Lassa Virus GP1 forms a binding site for host LAMP1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LAMP1 / CD107a antibody

 Reference Product  PubMed Publications
 EEA1 antibody  >44 publications with LAMP1 / CD107a and EEA1
 CD63 antibody  >34 publications with LAMP1 / CD107a and CD63
 EGFR antibody  >20 publications with LAMP1 / CD107a and EGFR
 RAB5A antibody  >8 publications with LAMP1 / CD107a and RAB5A
 NCAM1 antibody  >3 publications with LAMP1 / CD107a and NCAM1
 IL21 antibody  >1 publications with LAMP1 / CD107a and IL21
 RAB7A antibody  >1 publications with LAMP1 / CD107a and RAB7A

Pathways associated with anti-LAMP1 / CD107a antibody

 Products by Pathway  Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Lysosome Pathway antibodies  Lysosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Phagosome Pathway antibodies  Phagosome Pathway Diagram
 Senescence And Autophagy Pathway antibodies  Senescence And Autophagy Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram

Diseases associated with anti-LAMP1 / CD107a antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >66 publications with LAMP1 / CD107a and Nervous System Diseases
 Brain Diseases Antibodies  >57 publications with LAMP1 / CD107a and Brain Diseases
 Disease Models, Animal Antibodies  >49 publications with LAMP1 / CD107a and Disease Models, Animal
 Inflammation Antibodies  >24 publications with LAMP1 / CD107a and Inflammation
 Neoplasms, Experimental Antibodies  >22 publications with LAMP1 / CD107a and Neoplasms, Experimental
 Necrosis Antibodies  >22 publications with LAMP1 / CD107a and Necrosis
 Lung Diseases Antibodies  >20 publications with LAMP1 / CD107a and Lung Diseases
 Fibrosis Antibodies  >14 publications with LAMP1 / CD107a and Fibrosis
 Liver Diseases Antibodies  >12 publications with LAMP1 / CD107a and Liver Diseases
 Lung Neoplasms Antibodies  >12 publications with LAMP1 / CD107a and Lung Neoplasms

Organs/Tissues associated with anti-LAMP1 / CD107a antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >126 publications with LAMP1 / CD107a and Blood
 Brain Antibodies  >78 publications with LAMP1 / CD107a and Brain
 Liver Antibodies  >36 publications with LAMP1 / CD107a and Liver
 Bone Antibodies  >35 publications with LAMP1 / CD107a and Bone
 Lung Antibodies  >35 publications with LAMP1 / CD107a and Lung
 Kidney Antibodies  >29 publications with LAMP1 / CD107a and Kidney
 Vascular Antibodies  >29 publications with LAMP1 / CD107a and Vascular
 Nerve Antibodies  >29 publications with LAMP1 / CD107a and Nerve
 Heart Antibodies  >27 publications with LAMP1 / CD107a and Heart
 Muscle Antibodies  >26 publications with LAMP1 / CD107a and Muscle
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