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VILIP / VSNL1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249487

VSNL1 Antibody, Hippocalcin-like protein 3 Antibody, HLP3 Antibody, HUVISL1 Antibody, HPCAL3 Antibody, Visinin-like 1 Antibody, VISL1 Antibody, VILIP Antibody, VILIP-1 Antibody, Visinin-like protein 1 Antibody, VLP-1 Antibody Description: VILIP / VSNL1 is a… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
VILIP / VSNL1, Monoclonal Antibody
Full Product Name
Anti-VILIP / VSNL1 Antibody (clone 3A9) IHC-plus
Product Synonym Names
Mouse Monoclonal [clone 3A9] (IgG1) to Human VILIP / VSNL1; Human VILIP / VSNL1; VSNL1; Hippocalcin-like protein 3; HLP3; HUVISL1; HPCAL3; Visinin-like 1; VISL1; VILIP; VILIP-1; Visinin-like protein 1; VLP-1
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3A9
Host
Mouse
Species Reactivity
Mouse, Bovine, Rat, Human
Form/Format
PBS, 10 mM sodium azide.
Purity/Purification
Affinity purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Molecular Weight
22,142 Da
OMIM
600817
3D Structure
ModBase 3D Structure for P62760
Target Species
Human
Applications Tested/Suitable for anti-VILIP / VSNL1 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-VILIP / VSNL1 antibody
IF (1:500 - 1:1000)
IHC-P (10 ug/ml)
WB (1:1000 - 1:2000)

Immunohistochemistry (IHC) of anti-VILIP / VSNL1 antibody

Anti-VILIP / VSNL1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Mouse Anti-VILIP / VSNL1 Monoclonal Antibody – Cat# MBS249487

Immunohistochemistry (IHC) of anti-VILIP / VSNL1 antibody

Confocal image of adult rat cerebellum stained with VILIP / VSNL1 antibody (green), chicken polyclonal antibody to MAP2(red) and DNA (blue). The VILIP / VSNL1 antibody antibody reveals perikarya and synaptic regions in the neuron rich granular layer (bottom) and synapse rich molecular layer (top). Note that the large prominent Purkinje neurons at the junction of these two layers do not stain with this antibody, in line with the findings of others.
Mouse Anti-VILIP / VSNL1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249487

Western Blot (WB) of anti-VILIP / VSNL1 antibody

Western blot of bovine cerebellum homogenate stained with VILIP / VSNL1 antibody in lane 11. Note the strong clean band running at 22 kDa. Lane 10 shows the same material stained with our alternate antibody to VSNL1, binds to the same band.
Mouse Anti-VILIP / VSNL1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS249487

Other Notes

Small volumes of anti-VILIP / VSNL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VILIP / VSNL1 purchase

MBS249487 is an antibody targeting VILIP / VSNL1. Also known as Anti-VILIP / VSNL1 Antibody (clone 3A9) IHC-plus. Reactive in Mouse, Bovine, Rat, Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for VILIP / VSNL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
visinin-like protein 1
NCBI Official Synonym Full Names
visinin like 1
NCBI Official Symbol
VSNL1
NCBI Official Synonym Symbols
HLP3; VILIP; HPCAL3; HUVISL1; VILIP-1
UniProt Protein Name
Visinin-like protein 1
UniProt Synonym Protein Names
Hippocalcin-like protein 3; HLP3
UniProt Gene Name
VSNL1
UniProt Synonym Gene Names
VISL1; VILIP; VLP-1; HLP3
UniProt Entry Name
VISL1_HUMAN
NCBI Protein Information
visinin-like protein 1

NCBI Summary for VILIP / VSNL1

This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
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UniProt Comments for VILIP / VSNL1

VSNL1: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. Belongs to the recoverin family.

Chromosomal Location of Human Ortholog: 2p24.3

Cellular Component: cytosol; membrane

Molecular Function: calcium ion binding; protein binding

Biological Process: negative regulation of insulin secretion; positive regulation of exocytosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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