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4E-BP2 / EIF4EBP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249504

EIF4EBP2 Antibody, 4E-BP2 Antibody, 4EBP2 Antibody, EIF4E-binding protein 2 Antibody, PHASII Antibody Description: 4E-BP2 / EIF4EBP2 is a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
4E-BP2 / EIF4EBP2, Polyclonal Antibody
Full Product Name
Anti-4E-BP2 / EIF4EBP2 Antibody IHC-plus
Product Synonym Names
Rabbit Polyclonal (IgG) to Human 4E-BP2 / EIF4EBP2; Human 4E-BP2 / EIF4EBP2; 4EBP2; EIF4E-binding protein 2; PHASII
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Purity/Purification
Caprylic acid and ammonium sulfate precipitation
Specificity
Human 4E-BP2 / EIF4EBP2
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
3D Structure
ModBase 3D Structure for Q13542
Immunogen
4E-BP2 / EIF4EBP2 antibody was raised against recombinant human Eukaryotic translation initiation factor 4E-binding protein 2 protein.
Immunogen Description
Recombinant human Eukaryotic translation initiation factor 4E-binding protein 2 protein.
Immunogen Type
Recombinant protein
Target Species
Human
Applications Tested/Suitable for anti-4E-BP2 / EIF4EBP2 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-4E-BP2 / EIF4EBP2 antibody
IHC-P (10 ug/ml)

Immunohistochemistry - Paraffin (IHC) of anti-4E-BP2 / EIF4EBP2 antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-4E-BP2 / EIF4EBP2 Polyclonal Antibody – Cat# MBS249504

Immunohistochemistry - Paraffin (IHC) of anti-4E-BP2 / EIF4EBP2 antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-4E-BP2 / EIF4EBP2 Polyclonal Antibody, Immunohistochemistry - Paraffin (IHC) – Cat# MBS249504

Other Notes

Small volumes of anti-4E-BP2 / EIF4EBP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 4E-BP2 / EIF4EBP2 purchase

MBS249504 is an antibody targeting 4E-BP2 / EIF4EBP2. Also known as Anti-4E-BP2 / EIF4EBP2 Antibody IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for 4E-BP2 / EIF4EBP2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
eukaryotic translation initiation factor 4E-binding protein 2
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 4E binding protein 2
NCBI Official Symbol
EIF4EBP2
NCBI Official Synonym Symbols
4EBP2; PHASII
NCBI Protein Information
eukaryotic translation initiation factor 4E-binding protein 2

NCBI Summary for 4E-BP2 / EIF4EBP2

This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]
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UniProt Comments for 4E-BP2 / EIF4EBP2

4E-BP2: eukaryotic translation initiation factor 4E binding protein 2

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: 10q21-q22

Cellular Component: cytoplasm

Molecular Function: eukaryotic initiation factor 4E binding; protein binding; translation repressor activity

Biological Process: cAMP-mediated signaling; insulin receptor signaling pathway; memory; negative regulation of translational initiation; regulation of synaptic plasticity; regulation of synaptic transmission; social behavior; TOR signaling pathway; translation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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