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MRGPRX3 / MRGX3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249513

MRGPRX3 Antibody, MAS-related GPR, member X3 Antibody, Hdrr1 Antibody, HDRR2 Antibody, MRGX3 Antibody, SNSR1 Antibody, SNSR2 Antibody, Mas-related GPCR member X3 Antibody Description: Orphan receptor. Probably involved in the function of nociceptive neurons.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MRGPRX3 / MRGX3, Polyclonal Antibody
Full Product Name
Anti-MRGPRX3 / MRGX3 Antibody (aa89-138) IHC-plus
Product Synonym Names
Rabbit Polyclonal (IgG) to Human MRGPRX3 / MRGX3; Human MRGPRX3 / MRGX3; MAS-related GPR; member X3; Hdrr1; HDRR2; SNSR1; SNSR2; Mas-related GPCR member X3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
MRGX3 Antibodyantibody detects endogenous levels of MRGX3.
Preparation and Storage
Store at -20 degree C.
Molecular Weight
36,483 Da
OMIM
607229
3D Structure
ModBase 3D Structure for Q96LB0
Immunogen
MRGPRX3 / MRGX3 antibody was raised against synthetic peptide from human MRGX3 (aa89-138).
Immunogen Description
Synthetic peptide from human MRGX3 (aa89-138).
Antigen Modification
aa89-138
Target Species
Human
Applications Tested/Suitable for anti-MRGPRX3 / MRGX3 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-MRGPRX3 / MRGX3 antibody
ELISA (1:10000)
IHC-P (2.5 ug/mg lysate)
WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-MRGPRX3 / MRGX3 antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-MRGPRX3 / MRGX3 Polyclonal Antibody – Cat# MBS249513

Western Blot (WB) of anti-MRGPRX3 / MRGX3 antibody

Western blot of the lysates from 293 cells using MRGX3 antibody.
Rabbit Anti-MRGPRX3 / MRGX3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249513

Other Notes

Small volumes of anti-MRGPRX3 / MRGX3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MRGPRX3 / MRGX3 purchase

MBS249513 is an antibody targeting MRGPRX3 / MRGX3. Also known as Anti-MRGPRX3 / MRGX3 Antibody (aa89-138) IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MRGPRX3 / MRGX3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mas-related G-protein coupled receptor member X3
NCBI Official Synonym Full Names
MAS related GPR family member X3
NCBI Official Symbol
MRGPRX3
NCBI Official Synonym Symbols
GPCR; MRGX3; SNSR1; SNSR2
UniProt Protein Name
Mas-related G-protein coupled receptor member X3
UniProt Synonym Protein Names
Sensory neuron-specific G-protein coupled receptor 1/2
UniProt Gene Name
MRGPRX3
UniProt Synonym Gene Names
MRGX3; SNSR1; SNSR2
UniProt Entry Name
MRGX3_HUMAN
NCBI Protein Information
mas-related G-protein coupled receptor member X3

NCBI Summary for MRGPRX3 / MRGX3

This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009]

UniProt Comments for MRGPRX3 / MRGX3

MRGPRX3: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11p15.1

Cellular Component: integral to plasma membrane

Molecular Function: G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-MRGPRX3 / MRGX3 antibody

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