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AGPS Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249514

AGPS Antibody, ALDHPSY Antibody, ADAP-S Antibody, ADPS Antibody, Alkyl-DHAP synthase Antibody, Aging-associated protein 5 Antibody, ADAS Antibody, ADHAPS Antibody Description: Alkylglycerone phosphate synthase (AGPS) belongs to a group of peroxisomal enzymes… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AGPS, Polyclonal Antibody
Full Product Name
Anti-AGPS Antibody IHC-plus
Product Gene Name
anti-AGPS antibody
Product Synonym Names
Rabbit Polyclonal (IgG) to Human AGPS; Human AGPS; ALDHPSY; ADAP-S; ADPS; Alkyl-DHAP synthase; Aging-associated protein 5; ADAS; ADHAPS
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Rat, Human
Form/Format
PBS, pH 7.4, 0.02% sodium azide
Purity/Purification
Affinity purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
72,912 Da
OMIM
600121
3D Structure
ModBase 3D Structure for O00116
Immunogen
AGPS antibody was raised against recombinant protein
Immunogen Description
Recombinant protein
Immunogen Type
Recombinant protein
Target Species
Human
Applications Tested/Suitable for anti-AGPS antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-AGPS antibody
IHC-P (5 ug/ml)

Immunohistochemistry (IHC) of anti-AGPS antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-AGPS Polyclonal Antibody – Cat# MBS249514

Western Blot (WB) of anti-AGPS antibody

 
Rabbit Anti-AGPS Polyclonal Antibody, Western Blot (WB) – Cat# MBS249514

Other Notes

Small volumes of anti-AGPS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGPS purchase

MBS249514 is an antibody targeting AGPS. Also known as Anti-AGPS Antibody IHC-plus. Reactive in Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AGPS. It may not necessarily be applicable to this product.

NCBI GI #
4501993
NCBI GeneID
8540
NCBI Accession #
NP_003650.1
UniProt Primary Accession #
O00116
UniProt Secondary Accession #
Q2TU35; A5D8U9
UniProt Related Accession #
O00116
GenBank Nucleotide #
NM_003659.3
NCBI Official Full Name
alkyldihydroxyacetonephosphate synthase, peroxisomal
NCBI Official Synonym Full Names
alkylglycerone phosphate synthase
NCBI Official Symbol
AGPS
NCBI Official Synonym Symbols
ADAS; ADPS; ADAP-S; ADHAPS; ALDHPSY
UniProt Protein Name
Alkyldihydroxyacetonephosphate synthase, peroxisomal
UniProt Synonym Protein Names
Aging-associated gene 5 protein; Alkylglycerone-phosphate synthase
Protein Family
Alkyldihydroxyacetonephosphate synthase
UniProt Gene Name
AGPS
UniProt Synonym Gene Names
Alkyl-DHAP synthase
UniProt Entry Name
ADAS_HUMAN
NCBI Protein Information
alkyldihydroxyacetonephosphate synthase, peroxisomal

NCBI Summary for AGPS

This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for AGPS

AGPS: Defects in AGPS are the cause of rhizomelic chondrodysplasia punctata type 3 (RCDP3). RCDP3 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation. Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

Protein type: Lipid Metabolism - ether lipid; Oxidoreductase; Transferase; EC 2.5.1.26; Mitochondrial

Chromosomal Location of Human Ortholog: 2q31.2

Cellular Component: intracellular membrane-bound organelle; membrane; mitochondrion; nucleolus; peroxisomal matrix; peroxisomal membrane; peroxisome

Molecular Function: alkylglycerone-phosphate synthase activity; oxidoreductase activity, acting on CH-OH group of donors; protein binding

Biological Process: cellular lipid metabolic process; ether lipid biosynthetic process; lipid biosynthetic process

Disease: Rhizomelic Chondrodysplasia Punctata, Type 3
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Research Articles on AGPS

1. we optimized the BITC construction targeting alkylglycerone phosphate synthase (AGPS) by computer-aided design, and the derivants also showed anti-tumor potential in vitro.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AGPS antibody

 Reference Product  PubMed Publications
 GNPAT antibody  >6 publications with AGPS and GNPAT
 FAR1 antibody  >3 publications with AGPS and FAR1
 PEX5 antibody  >1 publications with AGPS and PEX5

Pathways associated with anti-AGPS antibody

 Products by Pathway  Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Ether Lipid Metabolism Pathway antibodies  Ether Lipid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Peroxisomal Lipid Metabolism Pathway antibodies  Peroxisomal Lipid Metabolism Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Plasmalogen Biosynthesis Pathway antibodies  Plasmalogen Biosynthesis Pathway Diagram
 Triacylglyceride Synthesis Pathway antibodies  Triacylglyceride Synthesis Pathway Diagram

Diseases associated with anti-AGPS antibody

 Disease Name  Pubmed Publications
 Weight Gain Antibodies  >6 publications with AGPS and Weight Gain
 Inflammation Antibodies  >4 publications with AGPS and Inflammation
 Congenital Abnormalities Antibodies  >4 publications with AGPS and Congenital Abnormalities
 Liver Diseases Antibodies  >4 publications with AGPS and Liver Diseases
 Weight Loss Antibodies  >3 publications with AGPS and Weight Loss
 Liver Neoplasms Antibodies  >3 publications with AGPS and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with AGPS and Carcinoma, Hepatocellular
 Disease Models, Animal Antibodies  >3 publications with AGPS and Disease Models, Animal
 Necrosis Antibodies  >3 publications with AGPS and Necrosis
 Fatty Liver Antibodies  >2 publications with AGPS and Fatty Liver

Organs/Tissues associated with anti-AGPS antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16 publications with AGPS and Blood
 Vascular Antibodies  >13 publications with AGPS and Vascular
 Intestine Antibodies  >11 publications with AGPS and Intestine
 Liver Antibodies  >10 publications with AGPS and Liver
 Kidney Antibodies  >4 publications with AGPS and Kidney
 Embryonic Tissue Antibodies  >4 publications with AGPS and Embryonic Tissue
 Spleen Antibodies  >4 publications with AGPS and Spleen
 Brain Antibodies  >4 publications with AGPS and Brain
 Lung Antibodies  >3 publications with AGPS and Lung
 Nerve Antibodies  >3 publications with AGPS and Nerve
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