• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CLPP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249555

CLPP Antibody, Endopeptidase Clp Antibody Description: Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
CLPP, Polyclonal Antibody
Full Product Name
Anti-CLPP Antibody (aa215-277) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal (IgG) to Human CLPP; Human CLPP; Endopeptidase Clp
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, pH 7.0, 10% glycerol, 0.01% Thimerosal
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
Human CLPP
Preparation and Storage
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
30,180 Da
OMIM
601119
3D Structure
ModBase 3D Structure for Q16740
Immunogen
CLPP antibody was raised against synthetic peptide corresponding to a region within amino acids 215 and 277 of CLPP (SwissProt Q16740).
Immunogen Description
Synthetic peptide corresponding to a region within amino acids 215 and 277 of CLPP (SwissProt Q16740).
Immunogen Type
Synthetic peptide
Antigen Modification
aa215-277
Target Species
Human
Applications Tested/Suitable for anti-CLPP antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-CLPP antibody
IHC-P (5 ug/ml)
WB (1:500 - 1:3000)

Immunohistochemistry (IHC) of anti-CLPP antibody

Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-CLPP Polyclonal Antibody – Cat# MBS249555

Western Blot (WB) of anti-CLPP antibody

Sample (30 ug of whole cell lysate). A:293T, B: A431, C: H1299. 10% SDS PAGE. CLPP antibody diluted at 1:1500
Rabbit Anti-CLPP Polyclonal Antibody, Western Blot (WB) – Cat# MBS249555

Other Notes

Small volumes of anti-CLPP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLPP purchase

MBS249555 is an antibody targeting CLPP. Also known as Anti-CLPP Antibody (aa215-277) IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CLPP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ATP-dependent Clp protease proteolytic subunit, mitochondrial
NCBI Official Synonym Full Names
caseinolytic mitochondrial matrix peptidase proteolytic subunit
NCBI Official Symbol
CLPP
NCBI Official Synonym Symbols
DFNB81; PRLTS3
UniProt Protein Name
ATP-dependent Clp protease proteolytic subunit, mitochondrial
UniProt Synonym Protein Names
Endopeptidase Clp
UniProt Gene Name
CLPP
UniProt Entry Name
CLPP_HUMAN
NCBI Protein Information
ATP-dependent Clp protease proteolytic subunit, mitochondrial

NCBI Summary for CLPP

The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]

UniProt Comments for CLPP

CLPP: Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Belongs to the peptidase S14 family.

Protein type: Mitochondrial; EC 3.4.21.92; Protease

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: identical protein binding; peptidase activity; protein binding; serine-type endopeptidase activity

Biological Process: protein homooligomerization; proteolysis involved in cellular protein catabolic process

Disease: Perrault Syndrome 3
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000