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IL1RL2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249599

IL1RL2 Antibody, IL-1Rrp2 Antibody, IL1R-rp2 Antibody, IL1RRP2 Antibody, Interleukin 1 receptor-like 2 Antibody, Interleukin-1 receptor-like 2 Antibody, IL-36R Antibody Description: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to… More details

$650 / 0.05 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
IL1RL2, Polyclonal Antibody
Full Product Name
Anti-IL1RL2 Antibody (Internal) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal (IgG) to Human IL1RL2; Human IL1RL2; IL-1Rrp2; IL1R-rp2; IL1RRP2; Interleukin 1 receptor-like 2; Interleukin-1 receptor-like 2; IL-36R
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
IL-1RL2 antibody is human, mouse and rat reactive. At least three isoforms of IL-1RL2 are known to exist; this antibody will detect all three isoforms. IL-1RL2 antibody is predicted to not cross-react with IL-1R or IL-1RL1.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Molecular Weight
51,658 Da
OMIM
604512
3D Structure
ModBase 3D Structure for Q9HB29
Immunogen
IL1RL2 antibody was raised against 16 amino acid peptide near the center of human IL-1RL2.
Immunogen Description
16 amino acid peptide near the center of human IL-1RL2.
Antigen Modification
Internal
Target Species
Human
Applications Tested/Suitable for anti-IL1RL2 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-IL1RL2 antibody
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-IL1RL2 antibody

Anti-IL1RL2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-IL1RL2 Polyclonal Antibody – Cat# MBS249599

Immunofluorescence (IF) of anti-IL1RL2 antibody

Immunofluorescence of IL-1RL2 in human small intestine tissue with IL-1RL2 antibody at 20 ug/ml.
Rabbit Anti-IL1RL2 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS249599

Western Blot (WB) of anti-IL1RL2 antibody

Western blot analysis of IL-1RL2 in human small intestine lysate with IL-1RL2 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-IL1RL2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249599

Other Notes

Small volumes of anti-IL1RL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL1RL2 purchase

MBS249599 is an antibody targeting IL1RL2. Also known as Anti-IL1RL2 Antibody (Internal) IHC-plus. Reactive in Mouse, Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL1RL2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-1 receptor-like 2
NCBI Official Synonym Full Names
interleukin 1 receptor like 2
NCBI Official Symbol
IL1RL2
NCBI Official Synonym Symbols
IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2
UniProt Protein Name
Interleukin-1 receptor-like 2
UniProt Synonym Protein Names
IL-36 receptor; IL-36R; Interleukin-1 receptor-related protein 2; IL-1Rrp2; IL1R-rp2
UniProt Gene Name
IL1RL2
UniProt Synonym Gene Names
IL1RRP2; IL-36R; IL-1Rrp2; IL1R-rp2
UniProt Entry Name
ILRL2_HUMAN
NCBI Protein Information
interleukin-1 receptor-like 2

NCBI Summary for IL1RL2

The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL1RL2

IL1RL2: Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q12

Cellular Component: integral to plasma membrane

Molecular Function: interleukin-1 receptor activity; interleukin-1, Type I, activating receptor activity

Biological Process: cellular defense response; cytokine and chemokine mediated signaling pathway; inflammatory response; innate immune response; positive regulation of interleukin-6 production; positive regulation of T cell differentiation; regulation of inflammatory response; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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