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AOX1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249610

AOX1 Antibody, AO Antibody, Aldehyde oxidase 1 Antibody, AOH1 Antibody, Aldehyde oxidase Antibody Description: Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AOX1 / Aldehyde Oxidase, Polyclonal Antibody
Full Product Name
Anti-AOX1 / Aldehyde Oxidase Antibody IHC-plus
Product Gene Name
anti-AOX1 antibody
Product Synonym Names
Rabbit Polyclonal (IgG) to Human AOX1 / Aldehyde Oxidase; Human AOX1 / Aldehyde Oxidase; AO; Aldehyde oxidase 1; AOH1; Aldehyde oxidase
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Purity/Purification
Caprylic acid and ammonium sulfate precipitation
Specificity
Human AOX1 / Aldehyde Oxidase
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
3D Structure
ModBase 3D Structure for Q06278
Immunogen
AOX1 / Aldehyde Oxidase antibody was raised against recombinant human Aldehyde oxidase protein.
Immunogen Description
Recombinant human Aldehyde oxidase protein.
Immunogen Type
Recombinant protein
Target Species
Human
Applications Tested/Suitable for anti-AOX1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-AOX1 antibody
IHC-P (10 ug/ml)

Immunohistochemistry - Paraffin (IHC) of anti-AOX1 antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-AOX1 Polyclonal Antibody – Cat# MBS249610

Immunohistochemistry - Paraffin (IHC) of anti-AOX1 antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-AOX1 Polyclonal Antibody, Immunohistochemistry - Paraffin (IHC) – Cat# MBS249610

Other Notes

Small volumes of anti-AOX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AOX1 purchase

MBS249610 is an antibody targeting AOX1. Also known as Anti-AOX1 / Aldehyde Oxidase Antibody IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AOX1. It may not necessarily be applicable to this product.

NCBI GI #
71773480
NCBI GeneID
316
NCBI Accession #
NP_001150.3
UniProt Primary Accession #
Q06278
UniProt Related Accession #
Q06278
GenBank Nucleotide #
NM_001159.3
NCBI Official Full Name
aldehyde oxidase
NCBI Official Synonym Full Names
aldehyde oxidase 1
NCBI Official Symbol
AOX1
NCBI Official Synonym Symbols
AO; AOH1
UniProt Protein Name
Aldehyde oxidase
UniProt Synonym Protein Names
Aldehyde oxidase 1; Azaheterocycle hydroxylase (EC:1.17.3.-)
Protein Family
Alcohol oxidase
UniProt Gene Name
AOX1
UniProt Synonym Gene Names
AO
NCBI Protein Information
aldehyde oxidase

NCBI Summary for AOX1

Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]

UniProt Comments for AOX1

AOX1: Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - tyrosine; EC 1.2.3.1; Oxidoreductase; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Amino Acid Metabolism - tryptophan; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - vitamin B6

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: cytoplasm; cytosol

Molecular Function: 2 iron, 2 sulfur cluster binding; aldehyde oxidase activity; electron carrier activity; FAD binding; iron ion binding; molybdopterin cofactor binding; NAD binding; oxidoreductase activity, acting on CH-OH group of donors; xanthine dehydrogenase activity

Biological Process: inflammatory response; vitamin B6 metabolic process; vitamin metabolic process; water-soluble vitamin metabolic process; xanthine catabolic process
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Research Articles on AOX1

1. Data suggest that substrate specificity of AOX1 includes GDC-0834, an inhibitor of Bruton's tyrosine kinase with potential non-steroidal anti-inflammatory agent activity; in liver cytosol, hydrolysis of GDC-0834 is primarily due to AOX1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AOX1 antibody

 Reference Product  PubMed Publications
 XDH antibody  >3 publications with AOX1 and XDH
 MOCOS antibody  >2 publications with AOX1 and MOCOS
 NNMT antibody  >1 publications with AOX1 and NNMT

Pathways associated with anti-AOX1 antibody

 Products by Pathway  Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 Nicotinate And Nicotinamide Metabolism Pathway antibodies  Nicotinate And Nicotinamide Metabolism Pathway Diagram
 Nicotinate And Nicotinamide Metabolism Pathway antibodies  Nicotinate And Nicotinamide Metabolism Pathway Diagram

Diseases associated with anti-AOX1 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >5 publications with AOX1 and Fatty Liver
 Liver Diseases Antibodies  >5 publications with AOX1 and Liver Diseases
 Prostatic Neoplasms Antibodies  >5 publications with AOX1 and Prostatic Neoplasms
 Cardiovascular Diseases Antibodies  >4 publications with AOX1 and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >4 publications with AOX1 and Neoplasms, Experimental
 Weight Loss Antibodies  >3 publications with AOX1 and Weight Loss
 Liver Neoplasms Antibodies  >3 publications with AOX1 and Liver Neoplasms
 Disease Models, Animal Antibodies  >3 publications with AOX1 and Disease Models, Animal
 Adenocarcinoma Antibodies  >3 publications with AOX1 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >2 publications with AOX1 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-AOX1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >28 publications with AOX1 and Liver
 Vascular Antibodies  >12 publications with AOX1 and Vascular
 Prostate Antibodies  >5 publications with AOX1 and Prostate
 Skin Antibodies  >4 publications with AOX1 and Skin
 Brain Antibodies  >3 publications with AOX1 and Brain
 Muscle Antibodies  >3 publications with AOX1 and Muscle
 Intestine Antibodies  >3 publications with AOX1 and Intestine
 Kidney Antibodies  >3 publications with AOX1 and Kidney
 Bone Antibodies  >2 publications with AOX1 and Bone
 Heart Antibodies  >2 publications with AOX1 and Heart
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