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DECR1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249632

DECR1 Antibody, 2,4-dienoyl-coa reductase Antibody, 4-enoyl-CoA reductase [NADPH] Antibody, 4-enoyl-CoA reductase Antibody, DECR Antibody, NADPH Antibody, SDR18C1 Antibody Description: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
DECR1, Polyclonal Antibody
Full Product Name
Anti-DECR1 Antibody (aa1-335) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal to Human DECR1; Human DECR1; 2,4-dienoyl-coa reductase; 4-enoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase; DECR; NADPH; SDR18C1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Human
Form/Format
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
Human DECR1
Preparation and Storage
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.
Molecular Weight
34,994 Da
OMIM
222745
3D Structure
ModBase 3D Structure for Q16698
Immunogen
DECR1 antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 335 of DECR1 (SwissProt Q16698). Percent identity by BLAST analysis: Human (100%); Rat (82%).
Immunogen Description
Recombinant fragment corresponding to a region within amino acids 1 and 335 of DECR1 (SwissProt Q16698). Percent identity by BLAST analysis: Human (100%); Rat (82%).
Immunogen Type
Recombinant protein
Antigen Modification
aa1-335
Target Species
Human
Applications Tested/Suitable for anti-DECR1 antibody
Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Western Blot (WB)
Application Notes for anti-DECR1 antibody
ICC (1:100 - 1:1000)
IHC-P (5 ug/ml)
WB (1:5000 - 1:20000)

Immunohistochemistry (IHC) of anti-DECR1 antibody

Human Kidney: Formalin Fixed, Paraffin Embedded (FFPE)
Rabbit Anti-DECR1 Polyclonal Antibody – Cat# MBS249632

Immunohistochemistry (IHC) of anti-DECR1 antibody

Human Liver: Formalin Fixed, Paraffin Embedded (FFPE)
Rabbit Anti-DECR1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249632

Immunocytochemistry (ICC) of anti-DECR1 antibody

Immunofluorescence of paraformaldehyde-fixed HeLa using DECR1 antibody at 1:200 dilution.
Rabbit Anti-DECR1 Polyclonal Antibody, Immunocytochemistry (ICC) – Cat# MBS249632

Western Blot (WB) of anti-DECR1 antibody

Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. DECR1 antibody diluted at 1:10000.
Rabbit Anti-DECR1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249632

Western Blot (WB) of anti-DECR1 antibody

Sample (20 ug of whole cell lysate). A: mouse liver. 10% SDS PAGE. DECR1 antibody diluted at 1:10000.
Rabbit Anti-DECR1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249632

Other Notes

Small volumes of anti-DECR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DECR1 purchase

MBS249632 is an antibody targeting DECR1. Also known as Anti-DECR1 Antibody (aa1-335) IHC-plus. Reactive in Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DECR1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
2,4-dienoyl-CoA reductase, mitochondrial
NCBI Official Synonym Full Names
2,4-dienoyl-CoA reductase 1, mitochondrial
NCBI Official Symbol
DECR1
NCBI Official Synonym Symbols
DECR; NADPH; SDR18C1
UniProt Protein Name
2,4-dienoyl-CoA reductase, mitochondrial
UniProt Synonym Protein Names
2,4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]; Short chain dehydrogenase/reductase family 18C member 1
UniProt Gene Name
DECR1
UniProt Synonym Gene Names
DECR; SDR18C1; 4-enoyl-CoA reductase [NADPH]
UniProt Entry Name
DECR_HUMAN
NCBI Protein Information
2,4-dienoyl-CoA reductase, mitochondrial

NCBI Summary for DECR1

This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]

UniProt Comments for DECR1

DECR1: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.

Protein type: Oxidoreductase; EC 1.3.1.34; Mitochondrial

Chromosomal Location of Human Ortholog: 8q21.3

Cellular Component: cytoplasm; mitochondrial matrix; mitochondrion; nucleoplasm; nucleus

Molecular Function: 2,4-dienoyl-CoA reductase (NADPH) activity; oxidoreductase activity, acting on NADH or NADPH

Biological Process: cellular lipid metabolic process; fatty acid beta-oxidation; protein homotetramerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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