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CPA1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249644

CPA1 Antibody, CPA Antibody, Carboxypeptidase A1 Antibody, Pancreatic carboxypeptidase A Antibody, Carboxypeptidase A Antibody Description: CPA1 / Carboxypeptidase A is a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
CPA1 / Carboxypeptidase A, Polyclonal Antibody
Full Product Name
Anti-CPA1 / Carboxypeptidase A Antibody (aa301-350) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal (IgG) to Human CPA1 / Carboxypeptidase A; Human CPA1 / Carboxypeptidase A; CPA; Carboxypeptidase A1; Pancreatic carboxypeptidase A; Carboxypeptidase A
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
Carboxypeptidase A1 Antibody detects endogenous levels of Carboxypeptidase A1.
Preparation and Storage
Store at -20 degree C.
Molecular Weight
47,140 Da
OMIM
114850
3D Structure
ModBase 3D Structure for P15085
Immunogen
CPA1 / Carboxypeptidase A antibody was raised against synthetic peptide derived from human Carboxypeptidase A1 (aa301-350).
Immunogen Description
Synthetic peptide derived from human Carboxypeptidase A1 (aa301-350).
Immunogen Type
Synthetic peptide
Antigen Modification
aa301-350
Target Species
Human
Applications Tested/Suitable for anti-CPA1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-CPA1 antibody
ELISA (1:10000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)

Immunohistochemistry - Paraffin (IHC) of anti-CPA1 antibody

Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-CPA1 Polyclonal Antibody – Cat# MBS249644

Other Notes

Small volumes of anti-CPA1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CPA1 purchase

MBS249644 is an antibody targeting CPA1. Also known as Anti-CPA1 / Carboxypeptidase A Antibody (aa301-350) IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CPA1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
carboxypeptidase A1 preproprotein
NCBI Official Synonym Full Names
carboxypeptidase A1
NCBI Official Symbol
CPA1
NCBI Official Synonym Symbols
CPA
UniProt Protein Name
Carboxypeptidase A1
Protein Family
UniProt Gene Name
CPA1
UniProt Synonym Gene Names
CPA
UniProt Entry Name
CBPA1_HUMAN
NCBI Protein Information
carboxypeptidase A1

NCBI Summary for CPA1

This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]
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UniProt Comments for CPA1

CPA1: Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Belongs to the peptidase M14 family.

Protein type: Secreted, signal peptide; EC 3.4.17.1; Protease; Secreted

Chromosomal Location of Human Ortholog: 7q32

Cellular Component: extracellular space

Molecular Function: metallocarboxypeptidase activity; zinc ion binding

Biological Process: proteolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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