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RAP2C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249652

RAP2C Antibody, Ras-related protein Rap-2c Antibody, Small GTPase RAP2C Antibody Description: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell… More details

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Product Overview

Product Name
RAP2C, Polyclonal Antibody
Full Product Name
Anti-RAP2C Antibody (aa97-146) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal (IgG) to Human RAP2C; Human RAP2C; Ras-related protein Rap-2c; Small GTPase RAP2C
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Human
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
RAP2C Antibody detects endogenous levels of total RAP2C protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
20,745 Da
3D Structure
ModBase 3D Structure for Q9Y3L5
Immunogen
RAP2C antibody was raised against synthetic peptide from human RAP2C (aa97-146).
Immunogen Description
Synthetic peptide from human RAP2C (aa97-146).
Antigen Modification
aa97-146
Target Species
Human
Applications Tested/Suitable for anti-RAP2C antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-RAP2C antibody
ELISA (1:10000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-RAP2C antibody

Anti-RAP2C antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-RAP2C Polyclonal Antibody – Cat# MBS249652

Western Blot (WB) of anti-RAP2C antibody

Western blot of extracts from Jurkat/MCF-7 cells, using RAP2C Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-RAP2C Polyclonal Antibody, Western Blot (WB) – Cat# MBS249652

Other Notes

Small volumes of anti-RAP2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAP2C purchase

MBS249652 is an antibody targeting RAP2C. Also known as Anti-RAP2C Antibody (aa97-146) IHC-plus. Reactive in Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAP2C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras-related protein Rap-2c isoform 1
NCBI Official Synonym Full Names
RAP2C, member of RAS oncogene family
NCBI Official Symbol
RAP2C
UniProt Protein Name
Ras-related protein Rap-2c
Protein Family
UniProt Gene Name
RAP2C
UniProt Entry Name
RAP2C_HUMAN
NCBI Protein Information
ras-related protein Rap-2c

NCBI Summary for RAP2C

The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
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UniProt Comments for RAP2C

RAP2C: Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription. Belongs to the small GTPase superfamily. Ras family.

Protein type: G protein; G protein, monomeric, Ras; G protein, monomeric

Chromosomal Location of Human Ortholog: Xq25

Cellular Component: cytoplasm; cytosol; plasma membrane; recycling endosome membrane; tight junction

Molecular Function: GDP binding; GTP binding; transcription coactivator activity

Biological Process: microvillus biogenesis; negative regulation of cell migration; positive regulation of protein amino acid autophosphorylation; Rap protein signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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