Goat Anti-CKB Polyclonal Antibody – Cat# MBS249660

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

CKB Antibody – Goat Polyclonal

Name: CKB Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS249660
Price: 625 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249660

CKB Antibody, CKBB Antibody, Creatine kinase-B Antibody, Creatine kinase, b chain Antibody, B-CK Antibody, Creatine kinase B chain Antibody, Creatine kinase B-type Antibody, Creatine kinase, brain Antibody Description: Reversibly catalyzes the transfer of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CKB / Creatine Kinase BB, Polyclonal Antibody

Full Product Name

Anti-CKB / Creatine Kinase BB Antibody IHC-plus

Product Gene Name

anti-CKB antibody

Product Synonym Names

Goat Polyclonal to Human CKB / Creatine Kinase BB; Human CKB / Creatine Kinase BB; CKBB; Creatine kinase-B; Creatine kinase; b chain; B-CK; Creatine kinase B chain; Creatine kinase B-type; Creatine kinase; brain

Clonality

Polyclonal

Host

Goat

Species Reactivity

Human

Form/Format

PBS, pH 7.4, 0.05% sodium azide

Purity/Purification

Purified IgG

Concentration

4.52 mg/ml (lot specific)

Specificity

Specific for human CK-BB. 50% cross-reaction with CK-MB

Preparation and Storage

Short term 4 degree C
Long term aliquot and store at -20 degree C
Avoid freeze thaw cycles.

Molecular Weight

42,644 Da

OMIM

123280

3D Structure

ModBase 3D Structure for P12277

Immunogen

CKB / Creatine Kinase BB antibody was raised against purified human brain CKBB.

Immunogen Description

Purified human brain CKBB.

Target Species

Human

Applications Tested/Suitable for anti-CKB antibody

Immunohistochemistry (IHC) Paraffin

Application Notes for anti-CKB antibody

IHC-P (5 ug/ml)

Other Notes

Small volumes of anti-CKB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CKB purchase

MBS249660 is an antibody targeting CKB. Also known as Anti-CKB / Creatine Kinase BB Antibody IHC-plus. Reactive in Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for CKB. It may not necessarily be applicable to this product.

NCBI GI #

21536286

NCBI GeneID

1152

NCBI Accession #

NP_001814.2

UniProt Primary Accession #

P12277

UniProt Secondary Accession #

Q2LE07; Q6FG40; Q9UC66; A8K236; B2R5R4

UniProt Related Accession #

P12277

GenBank Nucleotide #

NM_001823.4

NCBI Official Full Name

creatine kinase B-type

NCBI Official Synonym Full Names

creatine kinase, brain

NCBI Official Symbol

CKB

NCBI Official Synonym Symbols

BCK; B-CK; CKBB; HEL-211; HEL-S-29

UniProt Protein Name

Creatine kinase B-type

UniProt Synonym Protein Names

B-CK; Creatine kinase B chain

Protein Family

Creatine kinase

UniProt Gene Name

CKB

UniProt Synonym Gene Names

CKBB

UniProt Entry Name

KCRB_HUMAN

NCBI Protein Information

creatine kinase B-type

NCBI Summary for CKB

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]

UniProt Comments for CKB

CKB: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: Kinase, other; Amino Acid Metabolism - arginine and proline; EC 2.7.3.2

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: cytoplasm; cytosol; extracellular space; mitochondrion; myelin sheath

Molecular Function: ATP binding; creatine kinase activity; protein binding; ubiquitin protein ligase binding

Biological Process: cellular chloride ion homeostasis; creatine metabolic process; phosphorylation; polyamine metabolic process; substantia nigra development

Research Articles on CKB

1. CK-MB levels were higher after ERCP in non-ischemic patients compared with a myocardial ischemia group. Creatine phosphokinase levels did not differ significantly between groups.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CKB antibody

Reference Product	PubMed Publications
CKM antibody	>15 publications with CKB and CKM
ASB9 antibody	>2 publications with CKB and ASB9
LDHA antibody	>1 publications with CKB and LDHA
LDHB antibody	>1 publications with CKB and LDHB
GAMT antibody	>1 publications with CKB and GAMT

Pathways associated with anti-CKB antibody

Products by Pathway	Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Arginine And Proline Metabolism Pathway antibodies	Arginine And Proline Metabolism Pathway Diagram
Creatine Metabolism Pathway antibodies	Creatine Metabolism Pathway Diagram
Creatine Pathway antibodies	Creatine Pathway Diagram
Creatine Pathway antibodies	Creatine Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Amino Acids And Derivatives Pathway antibodies	Metabolism Of Amino Acids And Derivatives Pathway Diagram
Metabolism Of Polyamines Pathway antibodies	Metabolism Of Polyamines Pathway Diagram
Urea Cycle And Metabolism Of Amino Groups Pathway antibodies	Urea Cycle And Metabolism Of Amino Groups Pathway Diagram

Diseases associated with anti-CKB antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>19 publications with CKB and Brain Diseases
Nervous System Diseases Antibodies	>14 publications with CKB and Nervous System Diseases
Cardiovascular Diseases Antibodies	>10 publications with CKB and Cardiovascular Diseases
Heart Diseases Antibodies	>8 publications with CKB and Heart Diseases
Disease Models, Animal Antibodies	>6 publications with CKB and Disease Models, Animal
Movement Disorders Antibodies	>5 publications with CKB and Movement Disorders
Liver Diseases Antibodies	>5 publications with CKB and Liver Diseases
Adenocarcinoma Antibodies	>5 publications with CKB and Adenocarcinoma
Cognition Disorders Antibodies	>4 publications with CKB and Cognition Disorders
Neoplasms, Experimental Antibodies	>4 publications with CKB and Neoplasms, Experimental

Organs/Tissues associated with anti-CKB antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>64 publications with CKB and Brain
Blood Antibodies	>32 publications with CKB and Blood
Muscle Antibodies	>18 publications with CKB and Muscle
Heart Antibodies	>14 publications with CKB and Heart
Uterus Antibodies	>13 publications with CKB and Uterus
Liver Antibodies	>8 publications with CKB and Liver
Nerve Antibodies	>8 publications with CKB and Nerve
Lung Antibodies	>7 publications with CKB and Lung
Bone Antibodies	>6 publications with CKB and Bone
Embryonic Tissue Antibodies	>4 publications with CKB and Embryonic Tissue