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RHOBTB2 / DBC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249695

RHOBTB2 Antibody, DBC2 Antibody, KIAA0717 Antibody, p83 Antibody Description: The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for… More details

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Technical Datasheet View PDF
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Product Overview

Product Name
RHOBTB2 / DBC2, Polyclonal Antibody
Full Product Name
Anti-RHOBTB2 / DBC2 Antibody (aa61-110) IHC-plus
Product Synonym Names
Rabbit Polyclonal (IgG) to Human RHOBTB2 / DBC2; Human RHOBTB2 / DBC2; KIAA0717; p83
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Human
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
RHBT2 Antibody detects endogenous levels of total RHBT2 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
83,469 Da
OMIM
607352
Immunogen
RHOBTB2 / DBC2 antibody was raised against synthetic peptide from human RHBT2 (aa61-110).
Immunogen Description
Synthetic peptide from human RHBT2 (aa61-110).
Antigen Modification
aa61-110
Target Species
Human
Applications Tested/Suitable for anti-RHOBTB2 / DBC2 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-RHOBTB2 / DBC2 antibody
ELISA (1:5000)
IHC-P (10 ug/ml)
WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-RHOBTB2 / DBC2 antibody

Anti-RHOBTB2 / DBC2 antibody IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-RHOBTB2 / DBC2 Polyclonal Antibody – Cat# MBS249695

Western Blot (WB) of anti-RHOBTB2 / DBC2 antibody

Western blot of extracts from HepG2/HeLa cells, using RHBT2 Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-RHOBTB2 / DBC2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249695

Other Notes

Small volumes of anti-RHOBTB2 / DBC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RHOBTB2 / DBC2 purchase

MBS249695 is an antibody targeting RHOBTB2 / DBC2. Also known as Anti-RHOBTB2 / DBC2 Antibody (aa61-110) IHC-plus. Reactive in Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RHOBTB2 / DBC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
rho-related BTB domain-containing protein 2 isoform 3
NCBI Official Synonym Full Names
Rho-related BTB domain containing 2
NCBI Official Symbol
RHOBTB2
NCBI Official Synonym Symbols
DBC2
UniProt Protein Name
Rho-related BTB domain-containing protein 2
UniProt Synonym Protein Names
Deleted in breast cancer 2 gene protein; p83
UniProt Gene Name
RHOBTB2
UniProt Synonym Gene Names
DBC2; KIAA0717
UniProt Entry Name
RHBT2_HUMAN
NCBI Protein Information
rho-related BTB domain-containing protein 2

NCBI Summary for RHOBTB2 / DBC2

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for RHOBTB2 / DBC2

RHOBTB2: is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: G protein; G protein, monomeric, Rho; G protein, monomeric

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: cytosol; plasma membrane

Molecular Function: GTP binding

Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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