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RAB11FIP4 / RAB11-FIP4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249736

RAB11FIP4 Antibody, FIP4-Rab11 Antibody, KIAA1821 Antibody, ARFO2 Antibody, Arfophilin-2 Antibody, RAB11-FIP4 Antibody Description: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
RAB11FIP4 / RAB11-FIP4, Polyclonal Antibody
Full Product Name
Anti-RAB11FIP4 / RAB11-FIP4 Antibody (aa452-501) IHC-plus
Product Gene Name
anti-RAB11FIP4 / RAB11-FIP4 antibody
Product Synonym Names
Rabbit Polyclonal (IgG) to Human RAB11FIP4 / RAB11-FIP4; Human RAB11FIP4 / RAB11-FIP4; FIP4-Rab11; KIAA1821; ARFO2; Arfophilin-2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Human
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
RAB11FIP4 Antibody detects endogenous levels of total RAB11FIP4 protein.
Preparation and Storage
Store at -20 degree C for up to one year.
Molecular Weight
60,771 Da
OMIM
611999
3D Structure
ModBase 3D Structure for Q86YS3
Immunogen
RAB11FIP4 / RAB11-FIP4 antibody was raised against synthetic peptide from human RAB11FIP4 (aa452-501).
Immunogen Description
Synthetic peptide from human RAB11FIP4 (aa452-501).
Antigen Modification
aa452-501
Target Species
Human
Applications Tested/Suitable for anti-RAB11FIP4 / RAB11-FIP4 antibody
Immunohistochemistry (IHC), Western Blot (WB), ELISA (EIA)
Application Notes for anti-RAB11FIP4 / RAB11-FIP4 antibody
ELISA (1:40000)
IHC (10 ug/ml)
WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-RAB11FIP4 / RAB11-FIP4 antibody

Anti-RAB11FIP4 / RAB11-FIP4 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-RAB11FIP4 / RAB11-FIP4 Polyclonal Antibody – Cat# MBS249736

Western Blot (WB) of anti-RAB11FIP4 / RAB11-FIP4 antibody

Western blot of extracts from 293/COLO/HUVEC/HepG2/HT-29 cells, using RAB11FIP4 Antibody. The lane on the right is treated with the synthesized peptide.
Rabbit Anti-RAB11FIP4 / RAB11-FIP4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249736

Other Notes

Small volumes of anti-RAB11FIP4 / RAB11-FIP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB11FIP4 / RAB11-FIP4 purchase

MBS249736 is an antibody targeting RAB11FIP4 / RAB11-FIP4. Also known as Anti-RAB11FIP4 / RAB11-FIP4 Antibody (aa452-501) IHC-plus. Reactive in Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB11FIP4 / RAB11-FIP4. It may not necessarily be applicable to this product.

NCBI GI #
28195388
NCBI GeneID
84440
NCBI Accession #
NP_116321.2
UniProt Primary Accession #
Q86YS3
UniProt Secondary Accession #
Q52LI1; Q8N829; Q8NDT7; Q969D8
UniProt Related Accession #
Q86YS3
GenBank Nucleotide #
NM_032932.5
NCBI Official Full Name
rab11 family-interacting protein 4 isoform 1
NCBI Official Synonym Full Names
RAB11 family interacting protein 4 (class II)
NCBI Official Symbol
RAB11FIP4
NCBI Official Synonym Symbols
RAB11-FIP4
UniProt Protein Name
Rab11 family-interacting protein 4
UniProt Synonym Protein Names
Arfophilin-2
UniProt Gene Name
RAB11FIP4
UniProt Synonym Gene Names
ARFO2; KIAA1821; FIP4-Rab11; Rab11-FIP4
UniProt Entry Name
RFIP4_HUMAN
NCBI Protein Information
rab11 family-interacting protein 4

NCBI Summary for RAB11FIP4 / RAB11-FIP4

Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Apr 2008]
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UniProt Comments for RAB11FIP4 / RAB11-FIP4

RAB11FIP4: Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. In case of infection by HCMV (human cytomegalovirus), may participate in egress of the virus out of nucleus; this function is independent of ARF6. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cleavage furrow; endocytic vesicle; endosome; extracellular space; microtubule organizing center; midbody; recycling endosome membrane; spindle

Molecular Function: ADP-ribosylation factor binding; calcium ion binding; protein binding; protein homodimerization activity; Rab GTPase binding

Biological Process: cytokinesis; transport; viral reproduction
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Research Articles on RAB11FIP4 / RAB11-FIP4

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB11FIP4 / RAB11-FIP4 antibody

 Reference Product  PubMed Publications
 ARF6 antibody  >1 publications with RAB11FIP4 / RAB11-FIP4 and ARF6

Pathways associated with anti-RAB11FIP4 / RAB11-FIP4 antibody

 Products by Pathway  Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram

Diseases associated with anti-RAB11FIP4 / RAB11-FIP4 antibody

 Disease Name  Pubmed Publications
 Neural Tube Defects Antibodies  >1 publications with RAB11FIP4 / RAB11-FIP4 and Neural Tube Defects
 Congenital Abnormalities Antibodies  >1 publications with RAB11FIP4 / RAB11-FIP4 and Congenital Abnormalities
 Ovarian Neoplasms Antibodies  >1 publications with RAB11FIP4 / RAB11-FIP4 and Ovarian Neoplasms
 Abnormalities, Multiple Antibodies  >1 publications with RAB11FIP4 / RAB11-FIP4 and Abnormalities, Multiple
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