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PDCL3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249746

PDCL3 Antibody, HTPHLP Antibody, PHLP2A Antibody, VIAF1 Antibody, Viral IAP-associated factor 1 Antibody, PHLP3 Antibody, Phosducin-like protein 3 Antibody, PhPL3 Antibody, VIAF Antibody, IAP-associated factor VIAF1 Antibody, Phosducin-like 3 Antibody, VIAF-1… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PDCL3, Polyclonal Antibody
Full Product Name
Anti-PDCL3 Antibody (C-Terminus) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal to Human PDCL3; Human PDCL3; HTPHLP; PHLP2A; VIAF1; Viral IAP-associated factor 1; PHLP3; Phosducin-like protein 3; PhPL3; VIAF; IAP-associated factor VIAF1; Phosducin-like 3; VIAF-1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
PDCL3 antibody is human, mouse and rat reactive. PDCL3 antibody is predicted to not cross-react with other members of the PDCL protein family.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Molecular Weight
27,614 Da
OMIM
611678
3D Structure
ModBase 3D Structure for Q9H2J4
Immunogen
PDCL3 antibody was raised against pDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3.
Immunogen Description
PDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3.
Immunogen Type
Synthetic peptide
Antigen Modification
C-Terminus
Target Species
Human
Applications Tested/Suitable for anti-PDCL3 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-PDCL3 antibody
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-PDCL3 antibody

Immunohistochemistry of PDCL3 in mouse liver tissue with PDCL3 antibody at 5 ug/mL.
Rabbit Anti-PDCL3 Polyclonal Antibody – Cat# MBS249746

Immunohistochemistry (IHC) of anti-PDCL3 antibody

Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-PDCL3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249746

Immunohistochemistry (IHC) of anti-PDCL3 antibody

Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-PDCL3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249746

Immunofluorescence (IF) of anti-PDCL3 antibody

Immunofluorescence of PDCL3 in mouse liver tissue with PDCL3 antibody at 20 ug/mL.
Rabbit Anti-PDCL3 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS249746

Western Blot (WB) of anti-PDCL3 antibody

Western blot analysis of PDCL3 in human brain tissue lysate with PDCL3 antibody at 1 ug/ml.
Rabbit Anti-PDCL3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249746

Other Notes

Small volumes of anti-PDCL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDCL3 purchase

MBS249746 is an antibody targeting PDCL3. Also known as Anti-PDCL3 Antibody (C-Terminus) IHC-plus. Reactive in Mouse, Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDCL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phosducin-like protein 3
NCBI Official Synonym Full Names
phosducin like 3
NCBI Official Symbol
PDCL3
NCBI Official Synonym Symbols
VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A
UniProt Protein Name
Phosducin-like protein 3
UniProt Synonym Protein Names
HTPHLP; PhPL3; Viral IAP-associated factor 1; VIAF-1
UniProt Gene Name
PDCL3
UniProt Synonym Gene Names
PhLP2A; VIAF1; VIAF-1
UniProt Entry Name
PDCL3_HUMAN
NCBI Protein Information
phosducin-like protein 3

NCBI Summary for PDCL3

This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]
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UniProt Comments for PDCL3

PDCL3: Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. Belongs to the phosducin family.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; queuine tRNA-ribosyltransferase activity; vascular endothelial growth factor receptor 2 binding

Biological Process: angiogenesis; apoptosis; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; protein folding; queuosine biosynthetic process; regulation of peptidyl-tyrosine phosphorylation; viral reproduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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