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REPS1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249786

REPS1 Antibody, RalBP1-interacting protein 1 Antibody Description: REPS1 is a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in… More details

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Product Overview

Product Name
REPS1, Polyclonal Antibody
Full Product Name
Anti-REPS1 Antibody (aa579-628) IHC-plus
Product Gene Name
Product Synonym Names
Rabbit Polyclonal (IgG) to Human REPS1; Human REPS1; RalBP1-interacting protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
REPS1 Antibodyantibody detects endogenous levels of REPS1.
Preparation and Storage
Store at -20 degree C.
Molecular Weight
83,650 Da
OMIM
614825
3D Structure
ModBase 3D Structure for Q96D71
Immunogen
REPS1 antibody was raised against synthetic peptide from human REPS1 (aa579-628).
Immunogen Description
Synthetic peptide from human REPS1 (aa579-628).
Antigen Modification
aa579-628
Target Species
Human
Applications Tested/Suitable for anti-REPS1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-REPS1 antibody
ELISA (1:10000)
IHC-P (5 ug/ml)
WB (1:500 - 1:1000)

Immunohistochemistry (IHC) of anti-REPS1 antibody

Anti-REPS1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Rabbit Anti-REPS1 Polyclonal Antibody – Cat# MBS249786

Western Blot (WB) of anti-REPS1 antibody

Western blot of the lysates from K562 cells using REPS1 antibody.
Rabbit Anti-REPS1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249786

Other Notes

Small volumes of anti-REPS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for REPS1 purchase

MBS249786 is an antibody targeting REPS1. Also known as Anti-REPS1 Antibody (aa579-628) IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for REPS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ralBP1-associated Eps domain-containing protein 1 isoform a
NCBI Official Synonym Full Names
RALBP1 associated Eps domain containing 1
NCBI Official Symbol
REPS1
NCBI Official Synonym Symbols
RALBP1
UniProt Protein Name
RalBP1-associated Eps domain-containing protein 1
UniProt Synonym Protein Names
RalBP1-interacting protein 1
UniProt Gene Name
REPS1
UniProt Entry Name
REPS1_HUMAN
NCBI Protein Information
ralBP1-associated Eps domain-containing protein 1

NCBI Summary for REPS1

This gene encodes a signaling adaptor protein with two EH domains that interacts with proteins that participate in signaling, endocytosis and cytoskeletal changes. The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits. The encoded protein has also been shown to interact with amphiphysin, a cytoplasmic protein at the surface of synaptic vesicles. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
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UniProt Comments for REPS1

REPS1: a vesicle-associated protein that influences endocytosis through its ability to interact with Rab11FIP2 and RALBP1. An EGFR substrate that interacts with CRK and GRB2. May coordinate the cellular actions of activated EGF receptors and Ral-GTPases. Binding to RALBP1 does not affect its Ral-binding activity. Forms a complex with the SH3 domains of CRK and GRB2. Three alternatively spliced isoforms have been described.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 6q24.1

Cellular Component: coated pit; plasma membrane

Molecular Function: calcium ion binding; protein binding; SH3 domain binding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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