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C/EBP Delta / CEBPD (CEBPD) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249825

CEBPD Antibody, C/EBP-delta Antibody, C/EBP delta Antibody, CELF Antibody, CRP3 Antibody, NF-IL6-beta Antibody, Nuclear factor NF-IL6-beta Antibody Description: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to… More details

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Product Overview

Product Name
C/EBP Delta / CEBPD, Polyclonal Antibody
Full Product Name
Anti-C/EBP Delta / CEBPD Antibody (C-Terminus) IHC-plus
Product Gene Name
anti-CEBPD antibody
Product Synonym Names
Rabbit Polyclonal (IgG) to Human C/EBP Delta / CEBPD; Human C/EBP Delta / CEBPD; C/EBP-delta; C/EBP delta; CELF; CRP3; NF-IL6-beta; Nuclear factor NF-IL6-beta
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Form/Format
PBS, 0.02% sodium azide
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
Human CEBPD / CEBP Delta. Multiple transcript variants encoding different isoforms have been found for this gene.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Molecular Weight
28,467 Da
OMIM
116898
3D Structure
ModBase 3D Structure for P49716
Immunogen
C/EBP Delta / CEBPD antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CEBPD.
Immunogen Description
An 18 amino acid peptide near the carboxy terminus of human CEBPD.
Immunogen Type
Synthetic peptide
Antigen Modification
C-Terminus
Target Species
Human
Applications Tested/Suitable for anti-CEBPD antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes for anti-CEBPD antibody
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (0.5 - 1 ug/ml)

Immunohistochemistry (IHC) of anti-CEBPD antibody

Anti-C/EBP Delta / CEBPD antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-CEBPD Polyclonal Antibody – Cat# MBS249825

Immunohistochemistry (IHC) of anti-CEBPD antibody

Anti-C/EBP Delta / CEBPD antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Rabbit Anti-CEBPD Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249825

Immunofluorescence (IF) of anti-CEBPD antibody

Immunofluorescence of CEBPD in human spleen tissue with CEBPD antibody at 20 ug/ml.
Rabbit Anti-CEBPD Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS249825

Immunofluorescence (IF) of anti-CEBPD antibody

Immunofluorescence of CEBPD in human spleen tissue with CEBPD antibody at 20 µg/mL.
Rabbit Anti-CEBPD Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS249825

Western Blot (WB) of anti-CEBPD antibody

Western blot analysis of CEBPD in rat spleen tissue lysate with CEBPD antibody at 0.5 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Rabbit Anti-CEBPD Polyclonal Antibody, Western Blot (WB) – Cat# MBS249825

Other Notes

Small volumes of anti-CEBPD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CEBPD purchase

MBS249825 is an antibody targeting CEBPD. Also known as Anti-C/EBP Delta / CEBPD Antibody (C-Terminus) IHC-plus. Reactive in Mouse, Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CEBPD. It may not necessarily be applicable to this product.

NCBI GI #
28872798
NCBI GeneID
1052
NCBI Accession #
NP_005186.2
UniProt Primary Accession #
P49716
UniProt Secondary Accession #
Q14937; Q2M2X9
UniProt Related Accession #
P49716
GenBank Nucleotide #
NM_005195.3
NCBI Official Full Name
CCAAT/enhancer-binding protein delta
NCBI Official Synonym Full Names
CCAAT/enhancer binding protein delta
NCBI Official Symbol
CEBPD
NCBI Official Synonym Symbols
CELF; CRP3; C/EBP-delta; NF-IL6-beta
UniProt Protein Name
CCAAT/enhancer-binding protein delta
UniProt Synonym Protein Names
Nuclear factor NF-IL6-beta
Protein Family
CCAAT/enhancer-binding protein
UniProt Gene Name
CEBPD
UniProt Synonym Gene Names
NF-IL6-beta
UniProt Entry Name
CEBPD_HUMAN
NCBI Protein Information
CCAAT/enhancer-binding protein delta

NCBI Summary for CEBPD

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]
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UniProt Comments for CEBPD

C/EBP-delta: C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages. Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1. Interacts with PRDM16. Belongs to the bZIP family. C/EBP subfamily.

Protein type: DNA-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8p11.2-p11.1

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
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Research Articles on CEBPD

1. Authors found that CK2 bound to C/EBPdelta, which might help to target CK2 to the transcriptional machinery where it can phosphorylate other transcription factors or co-activators.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CEBPD antibody

 Reference Product  PubMed Publications
 CEBPA antibody  >37 publications with CEBPD and CEBPA
 CEBPB antibody  >27 publications with CEBPD and CEBPB
 STAT3 antibody  >11 publications with CEBPD and STAT3
 MYC antibody  >5 publications with CEBPD and MYC
 RELA antibody  >4 publications with CEBPD and RELA
 PPARG antibody  >3 publications with CEBPD and PPARG
 CREBBP antibody  >2 publications with CEBPD and CREBBP
 EP300 antibody  >1 publications with CEBPD and EP300

Pathways associated with anti-CEBPD antibody

 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 IL17 Signaling Pathway antibodies  IL17 Signaling Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Regulation Of Retinoblastoma Protein Pathway antibodies  Regulation Of Retinoblastoma Protein Pathway Diagram
 Transcriptional Regulation Of White Adipocyte Differentiation Pathway antibodies  Transcriptional Regulation Of White Adipocyte Differentiation Pathway Diagram
 Validated Targets Of C-MYC Transcriptional Repression Pathway antibodies  Validated Targets Of C-MYC Transcriptional Repression Pathway Diagram

Diseases associated with anti-CEBPD antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >45 publications with CEBPD and Inflammation
 Necrosis Antibodies  >20 publications with CEBPD and Necrosis
 Nervous System Diseases Antibodies  >18 publications with CEBPD and Nervous System Diseases
 Breast Neoplasms Antibodies  >13 publications with CEBPD and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >10 publications with CEBPD and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >10 publications with CEBPD and Disease Models, Animal
 Liver Diseases Antibodies  >9 publications with CEBPD and Liver Diseases
 Adenocarcinoma Antibodies  >8 publications with CEBPD and Adenocarcinoma
 Lung Diseases Antibodies  >8 publications with CEBPD and Lung Diseases
 Liver Neoplasms Antibodies  >8 publications with CEBPD and Liver Neoplasms

Organs/Tissues associated with anti-CEBPD antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >35 publications with CEBPD and Muscle
 Liver Antibodies  >25 publications with CEBPD and Liver
 Vascular Antibodies  >23 publications with CEBPD and Vascular
 Bone Antibodies  >23 publications with CEBPD and Bone
 Lung Antibodies  >20 publications with CEBPD and Lung
 Brain Antibodies  >18 publications with CEBPD and Brain
 Heart Antibodies  >17 publications with CEBPD and Heart
 Bone Marrow Antibodies  >12 publications with CEBPD and Bone Marrow
 Connective Tissue Antibodies  >10 publications with CEBPD and Connective Tissue
 Mammary Gland Antibodies  >8 publications with CEBPD and Mammary Gland
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