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RAB1A Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249833

RAB1A Antibody, GTP binding protein Rab1a Antibody, YPT1-related protein Antibody, Rab GTPase YPT1 homolog Antibody, RAB1 Antibody, Ras-related protein Rab-1A Antibody, YPT1 Antibody Description: The small GTPases Rab are key regulators of intracellular… More details

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Product Overview

Online Datasheet in PDF
Product Name
RAB1A, Polyclonal Antibody
Full Product Name
Anti-RAB1A Antibody (C-Terminus) IHC-plus
Product Gene Name
anti-RAB1A antibody
Product Synonym Names
Goat Polyclonal (IgG) to Mouse RAB1A; Mouse RAB1A; RAB1A; GTP binding protein Rab1a; YPT1-related protein; Rab GTPase YPT1 homolog; RAB1; Ras-related protein Rab-1A; YPT1
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Mouse, Rat, Human, Monkey
Non-Reactive Species: Canine
Form/Format
PBS, 20% glycerol, 0.05% sodium azide.
Purity/Purification
Immunoaffinity purified
Concentration
3 mg/ml (lot specific)
Specificity
Detects total Rab1 protein by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab1a and GFP-Rab1b cds.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Molecular Weight
13,903 Da
OMIM
179508
3D Structure
ModBase 3D Structure for P62820
Immunogen
RAB1A antibody was raised against purified recombinant peptides derived from within residues 110 aa to the C-terminus of mouse Rab1a and Rab1b produced in E Coli.
Immunogen Description
Purified recombinant peptides derived from within residues 110 aa to the C-terminus of mouse Rab1a and Rab1b produced in E Coli.
Immunogen Type
Recombinant protein
Antigen Modification
C-Terminus
Target Species
Mouse
Applications Tested/Suitable for anti-RAB1A antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-RAB1A antibody
IF (1:100 - 1:250)
IHC-P (5 ug/ml)
WB (1:250 - 1:2000)

Immunohistochemistry (IHC) of anti-RAB1A antibody

Anti-RAB1A / RAB1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Goat Anti-RAB1A Polyclonal Antibody – Cat# MBS249833

Immunohistochemistry (IHC) of anti-RAB1A antibody

Anti-RAB1A / RAB1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Goat Anti-RAB1A Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249833

Immunofluorescence (IF) of anti-RAB1A antibody

Immunofluorescence - anti-Rab1 antibody in COS-7 cells at 1:50 dilution. Cells were fixed with 4% of PFA.
Goat Anti-RAB1A Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS249833

Western Blot (WB) of anti-RAB1A antibody

Western blot. Anti-Rab1 antibody at 1:1000 dilution. 293HEK transfected lysate at 50 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.
Goat Anti-RAB1A Polyclonal Antibody, Western Blot (WB) – Cat# MBS249833

Other Notes

Small volumes of anti-RAB1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB1A purchase

MBS249833 is an antibody targeting RAB1A. Also known as Anti-RAB1A Antibody (C-Terminus) IHC-plus. Reactive in Mouse, Rat, Human, Monkey
Non-Reactive Species: Canine. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB1A. It may not necessarily be applicable to this product.

NCBI GI #
4758988
NCBI GeneID
5861
NCBI Accession #
NP_004152.1
UniProt Primary Accession #
P62820
UniProt Secondary Accession #
P11476; Q6FIE7; Q96N61; Q9Y3T2
UniProt Related Accession #
P62820
GenBank Nucleotide #
NM_004161.4
NCBI Official Full Name
ras-related protein Rab-1A isoform 1
NCBI Official Synonym Full Names
RAB1A, member RAS oncogene family
NCBI Official Symbol
RAB1A
NCBI Official Synonym Symbols
RAB1; YPT1
UniProt Protein Name
Ras-related protein Rab-1A
UniProt Synonym Protein Names
YPT1-related protein
Protein Family
Ras-related protein
UniProt Gene Name
RAB1A
UniProt Synonym Gene Names
RAB1
UniProt Entry Name
RAB1A_HUMAN
NCBI Protein Information
ras-related protein Rab-1A

NCBI Summary for RAB1A

This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008]
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UniProt Comments for RAB1A

RAB1A: Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, monomeric; G protein; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 2p14

Cellular Component: cytosol; early endosome; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane; melanosome

Molecular Function: GTP binding; GTPase activity; protein binding

Biological Process: autophagic vacuole formation; autophagy; cell migration; cellular protein metabolic process; cilium biogenesis; COPII coating of Golgi vesicle; defense response to bacterium; endocytosis; ER to Golgi vesicle-mediated transport; Golgi organization and biogenesis; growth hormone secretion; melanosome transport; mitotic cell cycle; post-translational protein modification; protein amino acid N-linked glycosylation via asparagine; small GTPase mediated signal transduction; vesicle transport along microtubule; vesicle-mediated transport; virus assembly
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Research Articles on RAB1A

1. Rab1A regulates anterograde melanosome transport by recruiting kinesin-1 to melanosomes through interaction with SKIP

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB1A antibody

 Reference Product  PubMed Publications
 RAB11B antibody  >1 publications with RAB1A and RAB11B

Pathways associated with anti-RAB1A antibody

 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 COPI-mediated Anterograde Transport Pathway antibodies  COPI-mediated Anterograde Transport Pathway Diagram
 COPII (Coat Protein 2) Mediated Vesicle Transport Pathway antibodies  COPII (Coat Protein 2) Mediated Vesicle Transport Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 ER To Golgi Anterograde Transport Pathway antibodies  ER To Golgi Anterograde Transport Pathway Diagram
 Golgi Cisternae Pericentriolar Stack Reorganization Pathway antibodies  Golgi Cisternae Pericentriolar Stack Reorganization Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 Legionellosis Pathway antibodies  Legionellosis Pathway Diagram
 M Phase Pathway antibodies  M Phase Pathway Diagram

Diseases associated with anti-RAB1A antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >4 publications with RAB1A and Cardiovascular Diseases
 Heart Diseases Antibodies  >3 publications with RAB1A and Heart Diseases
 Disease Models, Animal Antibodies  >3 publications with RAB1A and Disease Models, Animal
 Precancerous Conditions Antibodies  >2 publications with RAB1A and Precancerous Conditions
 Fibrosis Antibodies  >2 publications with RAB1A and Fibrosis
 Hypertrophy Antibodies  >2 publications with RAB1A and Hypertrophy
 Carcinoma, Hepatocellular Antibodies  >2 publications with RAB1A and Carcinoma, Hepatocellular
 Uterine Cervical Neoplasms Antibodies  >1 publications with RAB1A and Uterine Cervical Neoplasms
 Liver Diseases Antibodies  >1 publications with RAB1A and Liver Diseases
 Asthma Antibodies  >1 publications with RAB1A and Asthma

Organs/Tissues associated with anti-RAB1A antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >8 publications with RAB1A and Muscle
 Nerve Antibodies  >7 publications with RAB1A and Nerve
 Kidney Antibodies  >6 publications with RAB1A and Kidney
 Heart Antibodies  >6 publications with RAB1A and Heart
 Brain Antibodies  >6 publications with RAB1A and Brain
 Liver Antibodies  >5 publications with RAB1A and Liver
 Bone Antibodies  >4 publications with RAB1A and Bone
 Pancreas Antibodies  >3 publications with RAB1A and Pancreas
 Eye Antibodies  >3 publications with RAB1A and Eye
 Mouth Antibodies  >3 publications with RAB1A and Mouth
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