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PS20 / WFDC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249842

WFDC1 Antibody, Prostate stromal protein ps20 Antibody, PS20 Antibody, Ps20 growth inhibitor Antibody Description: PS20 / WFDC1 is a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
PS20 / WFDC1, Polyclonal Antibody
Full Product Name
Anti-PS20 / WFDC1 Antibody (aa147-177) IHC-plus
Product Synonym Names
Rabbit Polyclonal to Human PS20 / WFDC1; Human PS20 / WFDC1; Prostate stromal protein ps20; Ps20 growth inhibitor
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, 0.09% sodium azide
Purity/Purification
Immunoaffinity purified
Specificity
Human PS20 / WFDC1
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.
Molecular Weight
23,977 Da
OMIM
605322
3D Structure
ModBase 3D Structure for Q9HC57
Immunogen
PS20 / WFDC1 antibody was raised against kLH-conjugated synthetic peptide from C-terminal region of human WFDC1.
Immunogen Description
KLH-conjugated synthetic peptide from C-terminal region of human WFDC1.
Immunogen Type
Synthetic peptide
Antigen Modification
aa147-177
Target Species
Human
Applications Tested/Suitable for anti-PS20 / WFDC1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-PS20 / WFDC1 antibody
Flow Cytometry (1:10 - 1:50)
IHC-P (1:100)
WB (1:1000)

Immunohistochemistry - Paraffin (IHC) of anti-PS20 / WFDC1 antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-PS20 / WFDC1 Polyclonal Antibody – Cat# MBS249842

Immunohistochemistry - Paraffin (IHC) of anti-PS20 / WFDC1 antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-PS20 / WFDC1 Polyclonal Antibody, Immunohistochemistry - Paraffin (IHC) – Cat# MBS249842

Western Blot (WB) of anti-PS20 / WFDC1 antibody

WFDC1 Antibody (C-term H163) western blot of HeLa cell line lysates (35 ug/lane). The WFDC1 antibody detected the WFDC1 protein (arrow).
Rabbit Anti-PS20 / WFDC1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249842

Flow Cytometry (FC/FACS) of anti-PS20 / WFDC1 antibody

WFDC1 Antibody (C-term H163) flow cytometry of HeLa cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-PS20 / WFDC1 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS249842

Other Notes

Small volumes of anti-PS20 / WFDC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PS20 / WFDC1 purchase

MBS249842 is an antibody targeting PS20 / WFDC1. Also known as Anti-PS20 / WFDC1 Antibody (aa147-177) IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PS20 / WFDC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
WAP four-disulfide core domain protein 1 isoform 1
NCBI Official Synonym Full Names
WAP four-disulfide core domain 1
NCBI Official Symbol
WFDC1
NCBI Official Synonym Symbols
PS20
UniProt Protein Name
WAP four-disulfide core domain protein 1
UniProt Synonym Protein Names
Prostate stromal protein ps20; ps20 growth inhibitor
UniProt Gene Name
WFDC1
UniProt Synonym Gene Names
PS20
UniProt Entry Name
WFDC1_HUMAN
NCBI Protein Information
WAP four-disulfide core domain protein 1

NCBI Summary for PS20 / WFDC1

This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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UniProt Comments for PS20 / WFDC1

WFDC1: Has growth inhibitory activity.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: extracellular space

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: negative regulation of cell growth; negative regulation of epithelial cell proliferation; negative regulation of inflammatory response; regulation of cell growth; response to drug; response to estradiol stimulus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PS20 / WFDC1 antibody

 Reference Product  PubMed Publications
 CBFA2T3 antibody  >1 publications with PS20 / WFDC1 and CBFA2T3
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