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AMBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249850

AMBP Antibody, A1M Antibody, Alpha-1-microglobulin Antibody, Bikunin Antibody, HCP Antibody, IATIL Antibody, ITIL Antibody, HI30 Antibody, ITI Antibody, ITILC Antibody, Protein AMBP Antibody, Uronic-acid-rich protein Antibody, UTI Antibody, Trypstatin… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
AMBP / Bikunin, Polyclonal Antibody
Full Product Name
Anti-AMBP / Bikunin Antibody IHC-plus
Product Gene Name
anti-AMBP antibody
Product Synonym Names
Rabbit Polyclonal (IgG) to Human AMBP / Bikunin; Human AMBP / Bikunin; A1M; Alpha-1-microglobulin; Bikunin; HCP; IATIL; ITIL; HI30; ITI; ITILC; Protein AMBP; Uronic-acid-rich protein; UTI; Trypstatin; Uristatin; EDC1; Growth-inhibiting protein 19; Protein HC
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Purity/Purification
Caprylic acid and ammonium sulfate precipitation
Specificity
Human Bikunin / AMBP
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Molecular Weight
38,999 Da
OMIM
176870
3D Structure
ModBase 3D Structure for P02760
Immunogen
AMBP / Bikunin antibody was raised against recombinant human Protein AMBP protein.
Immunogen Description
Recombinant human Protein AMBP protein.
Immunogen Type
Recombinant protein
Target Species
Human
Applications Tested/Suitable for anti-AMBP antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-AMBP antibody
IHC-P (10 ug/ml)

Immunohistochemistry - Paraffin (IHC) of anti-AMBP antibody

Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-AMBP Polyclonal Antibody – Cat# MBS249850

Immunohistochemistry - Paraffin (IHC) of anti-AMBP antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-AMBP Polyclonal Antibody, Immunohistochemistry - Paraffin (IHC) – Cat# MBS249850

Other Notes

Small volumes of anti-AMBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMBP purchase

MBS249850 is an antibody targeting AMBP. Also known as Anti-AMBP / Bikunin Antibody IHC-plus. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AMBP. It may not necessarily be applicable to this product.

NCBI GI #
4502067
NCBI GeneID
259
NCBI Accession #
NP_001624.1
UniProt Primary Accession #
P02760
UniProt Secondary Accession #
P00977; P02759; P78491; Q2TU33; Q5TBD7; Q9UC58; Q9UDI8
UniProt Related Accession #
P02760
GenBank Nucleotide #
NM_001633.3
NCBI Official Full Name
protein AMBP preproprotein
NCBI Official Synonym Full Names
alpha-1-microglobulin/bikunin precursor
NCBI Official Symbol
AMBP
NCBI Official Synonym Symbols
A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
UniProt Protein Name
Protein AMBP
UniProt Synonym Protein Names
Alpha-1-microglobulin; Protein HC
Protein Family
Protein
UniProt Gene Name
AMBP
UniProt Synonym Gene Names
HCP; ITIL; Protein HC; ITI-LC
UniProt Entry Name
AMBP_HUMAN
NCBI Protein Information
protein AMBP

NCBI Summary for AMBP

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]
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UniProt Comments for AMBP

AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q32-q33

Cellular Component: cell surface; extracellular region; extracellular space; intracellular membrane-bound organelle; plasma membrane

Molecular Function: calcium channel inhibitor activity; calcium oxalate binding; heme binding; IgA binding; protein binding; protein homodimerization activity; serine-type endopeptidase inhibitor activity

Biological Process: cell adhesion; female pregnancy; heme catabolic process; negative regulation of immune response; negative regulation of JNK cascade; protein catabolic process; protein-chromophore linkage; receptor-mediated endocytosis; viral reproduction
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Research Articles on AMBP

1. results indicate a reduced UTI level in CSF of MS and NMO patients. The levels were associated with the severity of the two demyelinating diseases during relapse

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AMBP antibody

 Reference Product  PubMed Publications
 ALB antibody  >2 publications with AMBP and ALB
 SERPINC1 antibody  >2 publications with AMBP and SERPINC1
 SERPINA1 antibody  >1 publications with AMBP and SERPINA1
 ITIH1 antibody  >1 publications with AMBP and ITIH1

Pathways associated with anti-AMBP antibody

 Products by Pathway  Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Scavenging Of Heme From Plasma Pathway antibodies  Scavenging Of Heme From Plasma Pathway Diagram
 Vesicle-mediated Transport Pathway antibodies  Vesicle-mediated Transport Pathway Diagram

Diseases associated with anti-AMBP antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >63 publications with AMBP and Cardiovascular Diseases
 Hypertension Antibodies  >46 publications with AMBP and Hypertension
 Inflammation Antibodies  >23 publications with AMBP and Inflammation
 Necrosis Antibodies  >16 publications with AMBP and Necrosis
 Kidney Diseases Antibodies  >13 publications with AMBP and Kidney Diseases
 Heart Diseases Antibodies  >12 publications with AMBP and Heart Diseases
 Hemorrhage Antibodies  >9 publications with AMBP and Hemorrhage
 Liver Diseases Antibodies  >7 publications with AMBP and Liver Diseases
 Drug-Induced Liver Injury Antibodies  >6 publications with AMBP and Drug-Induced Liver Injury
 Disease Models, Animal Antibodies  >5 publications with AMBP and Disease Models, Animal

Organs/Tissues associated with anti-AMBP antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >35 publications with AMBP and Heart
 Liver Antibodies  >29 publications with AMBP and Liver
 Kidney Antibodies  >23 publications with AMBP and Kidney
 Intestine Antibodies  >14 publications with AMBP and Intestine
 Brain Antibodies  >13 publications with AMBP and Brain
 Muscle Antibodies  >7 publications with AMBP and Muscle
 Lung Antibodies  >5 publications with AMBP and Lung
 Pancreas Antibodies  >3 publications with AMBP and Pancreas
 Embryonic Tissue Antibodies  >2 publications with AMBP and Embryonic Tissue
 Spleen Antibodies  >1 publications with AMBP and Spleen
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