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SPAG16 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249863

SPAG16 Antibody, Pf20 protein homolog Antibody, WDR29 Antibody, PF20 Antibody, Sperm associated antigen 16 Antibody, WD repeat domain 29 Antibody Description: Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit… More details

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Product Overview

Product Name
SPAG16, Polyclonal Antibody
Full Product Name
Anti-SPAG16 Antibody (Internal) IHC-plus
Product Gene Name
Product Synonym Names
Goat Polyclonal to Human SPAG16; Human SPAG16; Pf20 protein homolog; WDR29; PF20; Sperm associated antigen 16; WD repeat domain 29
Clonality
Polyclonal
Host
Goat
Species Reactivity
Mouse, Rat, Pig, Horse, Human
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Purity/Purification
Immunoaffinity purified
Concentration
0.5 mg/ml (lot specific)
Specificity
Human SPAG16. This antibody is expected to recognize isoform 1 (NP_078808.3) only.
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.
Molecular Weight
39,739 Da
OMIM
612173
3D Structure
ModBase 3D Structure for Q8N0X2
Immunogen
SPAG16 antibody was raised against synthetic peptide C-KLHYASYEPTIR from an internal region of human SPAG16 (NP_078808.3). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Mouse, Rat, Panda, Horse, Pig, Opossum (100%); Marmoset, Hamster, Bovine (92%).
Immunogen Description
Synthetic peptide C-KLHYASYEPTIR from an internal region of human SPAG16 (NP_078808.3). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Mouse, Rat, Panda, Horse, Pig, Opossum (100%); Marmoset, Hamster, Bovine (92%).
Immunogen Type
Synthetic peptide - KLH conjugated
Antigen Modification
Internal
Target Species
Human
Applications Tested/Suitable for anti-SPAG16 antibody
Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes for anti-SPAG16 antibody
ELISA (1:32000)
IHC-P (5 ug/ml)

Immunohistochemistry (IHC) of anti-SPAG16 antibody

Human, TestisL Formalin-Fixed Paraffin-Embedded (FFPE)
Goat Anti-SPAG16 Polyclonal Antibody – Cat# MBS249863

Other Notes

Small volumes of anti-SPAG16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SPAG16 purchase

MBS249863 is an antibody targeting SPAG16. Also known as Anti-SPAG16 Antibody (Internal) IHC-plus. Reactive in Mouse, Rat, Pig, Horse, Human. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for SPAG16. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
sperm-associated antigen 16 protein isoform 1
NCBI Official Synonym Full Names
sperm associated antigen 16
NCBI Official Symbol
SPAG16
NCBI Official Synonym Symbols
PF20; WDR29
UniProt Protein Name
Sperm-associated antigen 16 protein
UniProt Synonym Protein Names
Pf20 protein homolog
UniProt Gene Name
SPAG16
UniProt Synonym Gene Names
PF20
UniProt Entry Name
SPG16_HUMAN
NCBI Protein Information
sperm-associated antigen 16 protein

NCBI Summary for SPAG16

Cilia and flagella are comprised of a microtubular backbone, the axoneme, which is organized by the basal body and surrounded by plasma membrane. SPAG16 encodes 2 major proteins that associate with the axoneme of sperm tail and the nucleus of postmeiotic germ cells, respectively (Zhang et al., 2007 [PubMed 17699735]).[supplied by OMIM, Jul 2008]
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UniProt Comments for SPAG16

SPAG16: Necessary for sperm flagellar function. Plays a role in motile ciliogenesis. May help to recruit STK36 to the cilium or apical surface of the cell to initiate subsequent steps of construction of the central pair apparatus of motile cilia. 5 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2q34

Cellular Component: axoneme; cytoskeleton; nucleus

Molecular Function: protein kinase binding

Biological Process: axoneme biogenesis; cilium biogenesis; microtubule sliding; sperm axoneme assembly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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