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MTERF3 / MTERFD1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249870

MTERF3 Antibody, CGI-12 Antibody, MTERF domain containing 1 Antibody, MTERFD1 Antibody Description: Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial… More details

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Product Overview

Product Name
MTERF3 / MTERFD1, Polyclonal Antibody
Full Product Name
Anti-MTERF3 / MTERFD1 Antibody (C-Terminus) IHC-plus
Product Synonym Names
Rabbit Polyclonal (IgG) to Human MTERF3 / MTERFD1; Human MTERF3 / MTERFD1; CGI-12; MTERF domain containing 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Mouse, Human
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
At least three isoforms of MTERFD1 are known to exist. MTERFD1 antibody is predicted to not cross-react with other MTERFD protein family members.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Molecular Weight
34,358 Da
3D Structure
ModBase 3D Structure for Q96E29
Immunogen
MTERF3 / MTERFD1 antibody was raised against 17 amino acid peptide near the carboxy terminus of human MTERFD1.
Immunogen Description
17 amino acid peptide near the carboxy terminus of human MTERFD1.
Antigen Modification
C-Terminus
Target Species
Human
Applications Tested/Suitable for anti-MTERF3 / MTERFD1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-MTERF3 / MTERFD1 antibody
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-MTERF3 / MTERFD1 antibody

Anti-MTERFD1 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Rabbit Anti-MTERF3 / MTERFD1 Polyclonal Antibody – Cat# MBS249870

Western Blot (WB) of anti-MTERF3 / MTERFD1 antibody

Western blot analysis of MTERFD1 in 3T3 cell lysate with MTERFD1 antibody at (A) 1 and (B) 2 ug/ml.
Rabbit Anti-MTERF3 / MTERFD1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS249870

Other Notes

Small volumes of anti-MTERF3 / MTERFD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTERF3 / MTERFD1 purchase

MBS249870 is an antibody targeting MTERF3 / MTERFD1. Also known as Anti-MTERF3 / MTERFD1 Antibody (C-Terminus) IHC-plus. Reactive in Mouse, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MTERF3 / MTERFD1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transcription termination factor 3, mitochondrial isoform 1
NCBI Official Synonym Full Names
mitochondrial transcription termination factor 3
NCBI Official Symbol
MTERF3
NCBI Official Synonym Symbols
CGI-12; MTERFD1
UniProt Protein Name
Transcription termination factor 3, mitochondrial
UniProt Synonym Protein Names
Mitochondrial transcription termination factor 3; mTERF3; mTERF domain-containing protein 1, mitochondrial
UniProt Gene Name
MTERF3
UniProt Synonym Gene Names
MTERFD1; mTERF3
UniProt Entry Name
MTEF3_HUMAN
NCBI Protein Information
transcription termination factor 3, mitochondrial

UniProt Comments for MTERF3 / MTERFD1

MTERFD1: Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function. Belongs to the mTERF family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 8q22.1

Cellular Component: mitochondrial outer membrane; mitochondrion

Molecular Function: double-stranded DNA binding; protein binding

Biological Process: macroautophagy; macromitophagy; negative regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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