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DEPTOR / DEPDC6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS249957

DEPTOR Antibody, DEP.6 Antibody, DEPDC6 Antibody, DEP domain containing 6 Antibody Description: Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. More details

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Testing Data View PDF
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Product Overview

Product Name
DEPTOR / DEPDC6, Polyclonal Antibody
Full Product Name
Anti-DEPTOR / DEPDC6 Antibody (Internal) IHC-plus
Product Synonym Gene Name
DEPTOR
Product Synonym Names
Rabbit Polyclonal to Human DEPTOR / DEPDC6; Human DEPTOR / DEPDC6; DEP.6; DEP domain containing 6
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, Rat, Human
Form/Format
PBS, 0.02% sodium azide.
Purity/Purification
Immunoaffinity purified
Concentration
1 mg/ml (lot specific)
Specificity
DEPTOR antibody is human, mouse and rat reactive. At least three isoforms of DEPTOR are known to exist; this antibody will detect all three isoforms.
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Molecular Weight
34,006 Da
OMIM
612974
3D Structure
ModBase 3D Structure for Q8TB45
Immunogen
DEPTOR / DEPDC6 antibody was raised against dEPTOR antibody was raised against a 16 amino acid peptide near the center of human DEPTOR.
Immunogen Description
DEPTOR antibody was raised against a 16 amino acid peptide near the center of human DEPTOR.
Immunogen Type
Synthetic peptide
Antigen Modification
Internal
Target Species
Human
Applications Tested/Suitable for anti-DEPTOR / DEPDC6 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB), ELISA (EIA)
Application Notes for anti-DEPTOR / DEPDC6 antibody
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)

Immunohistochemistry (IHC) of anti-DEPTOR / DEPDC6 antibody

Human Small Intestine, Myenteric Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-DEPTOR / DEPDC6 Polyclonal Antibody – Cat# MBS249957

Immunohistochemistry (IHC) of anti-DEPTOR / DEPDC6 antibody

Human Colon, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-DEPTOR / DEPDC6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS249957

Other Notes

Small volumes of anti-DEPTOR / DEPDC6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DEPTOR / DEPDC6 purchase

MBS249957 is an antibody targeting DEPTOR / DEPDC6. Also known as Anti-DEPTOR / DEPDC6 Antibody (Internal) IHC-plus. Reactive in Mouse, Rat, Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DEPTOR / DEPDC6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DEP domain-containing mTOR-interacting protein isoform 1
NCBI Official Synonym Full Names
DEP domain containing MTOR-interacting protein
NCBI Official Symbol
DEPTOR
NCBI Official Synonym Symbols
DEP.6; DEPDC6
UniProt Protein Name
DEP domain-containing mTOR-interacting protein
UniProt Synonym Protein Names
DEP domain-containing protein 6
UniProt Gene Name
DEPTOR
UniProt Synonym Gene Names
DEPDC6
UniProt Entry Name
DPTOR_HUMAN
NCBI Protein Information
DEP domain-containing mTOR-interacting protein

UniProt Comments for DEPTOR / DEPDC6

DEPTOR: Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 8q24.12

Cellular Component: intracellular

Molecular Function: protein binding

Biological Process: negative regulation of cell size; negative regulation of protein kinase activity; negative regulation of TOR signaling pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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