Rabbit Anti-TACC2 Polyclonal Antibody – Cat# MBS2520889

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TACC2 Polyclonal Antibody at dilution 1:40

TACC2 Antibody – Rabbit Polyclonal

Name: TACC2 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2520889
Price: 160 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2520889

Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a… More details

$160 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TACC2, Polyclonal Antibody

Full Product Name

TACC2 Polyclonal Antibody

Product Gene Name

anti-TACC2 antibody

Product Synonym Names

AZU-1; ECTACC

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Antigen affinity purification

Concentration

2.4mg/mL (lot specific)

Preparation and Storage

Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Molecular Weight

108,690 Da

OMIM

605302

Immunogen

Synthetic peptide of human TACC2

Buffer

PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Product Categories/Family for anti-TACC2 antibody

Cell biology; Epigenetics

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-TACC2 antibody

ELISA (EIA), Immunohistochemistry (IHC)

Application Notes for anti-TACC2 antibody

IHC: 1:25-1:100

Other Notes

Small volumes of anti-TACC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TACC2 purchase

MBS2520889 is an antibody targeting TACC2. Also known as TACC2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TACC2. It may not necessarily be applicable to this product.

NCBI GI #

630044897

NCBI GeneID

10579

NCBI Accession #

NP_001278808.1

UniProt Secondary Accession #

Q4VXL0; Q4VXL3; Q4VXL6; Q4VXL7; Q5U5T7; Q86WG6; Q86WG7; Q8TCK9; Q9BVQ1; Q9NZ41; Q9NZR5

UniProt Related Accession #

O95359

GenBank Nucleotide #

NM_001291879.1

NCBI Official Full Name

transforming acidic coiled-coil-containing protein 2 isoform h

NCBI Official Synonym Full Names

transforming, acidic coiled-coil containing protein 2

NCBI Official Symbol

TACC2

NCBI Official Synonym Symbols

AZU-1; ECTACC

UniProt Protein Name

Transforming acidic coiled-coil-containing protein 2

UniProt Synonym Protein Names

Anti-Zuai-1; AZU-1

Protein Family

Transforming acidic coiled-coil-containing protein

UniProt Gene Name

TACC2

UniProt Synonym Gene Names

AZU-1

UniProt Entry Name

TACC2_HUMAN

NCBI Protein Information

transforming acidic coiled-coil-containing protein 2; anti zuai-1

UniProt Comments for TACC2

TACC2: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors. May play a role in organizing centrosomal microtubules. May act as a tumor suppressor protein. May represent a tumor progression marker. Belongs to the TACC family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 10q26

Cellular Component: nucleoplasm; microtubule cytoskeleton; cytoplasm; nucleolus; microtubule organizing center; nucleus

Molecular Function: protein domain specific binding; nuclear hormone receptor binding

Biological Process: regulation of microtubule-based process; cell proliferation; astral microtubule organization and biogenesis; neurogenesis; microtubule cytoskeleton organization and biogenesis; cerebral cortex development; interkinetic nuclear migration

Research Articles on TACC2

1. Data suggest that TACC2 is highly expressed in prostate cancer cells and contributes to cell cycle progression and cell proliferation in androgen-nonresponsive prostate cancer cells; overexpression of TACC2 leads to recurrence of prostate cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TACC2 antibody

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>7 publications with TACC2 and Breast Neoplasms
Cardiovascular Diseases Antibodies	>2 publications with TACC2 and Cardiovascular Diseases
Anemia Antibodies	>1 publications with TACC2 and Anemia
Precancerous Conditions Antibodies	>1 publications with TACC2 and Precancerous Conditions
Heart Diseases Antibodies	>1 publications with TACC2 and Heart Diseases
Inflammation Antibodies	>1 publications with TACC2 and Inflammation
Necrosis Antibodies	>1 publications with TACC2 and Necrosis
Hyperplasia Antibodies	>1 publications with TACC2 and Hyperplasia

Organs/Tissues associated with anti-TACC2 antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>5 publications with TACC2 and Kidney
Prostate Antibodies	>4 publications with TACC2 and Prostate
Heart Antibodies	>4 publications with TACC2 and Heart
Muscle Antibodies	>4 publications with TACC2 and Muscle
Brain Antibodies	>4 publications with TACC2 and Brain
Mammary Gland Antibodies	>3 publications with TACC2 and Mammary Gland
Embryonic Tissue Antibodies	>2 publications with TACC2 and Embryonic Tissue
Bone Antibodies	>2 publications with TACC2 and Bone
Testis Antibodies	>1 publications with TACC2 and Testis
Vascular Antibodies	>1 publications with TACC2 and Vascular