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PRKG2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2521199

cGKII (cGMP-dependent protein kinase type II) is a major receptor of intracellular cGMP and mediates a plethora of physiological responses. cGKII contains a conserved leucine zipper motif at the amino-terminus. It is expressed in small intestine, colon,… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRKG2, Polyclonal Antibody
Full Product Name
PRKG2 Polyclonal Antibody
Product Gene Name
Product Synonym Names
cGKII; PRKGR2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
0.8mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
84,398 Da
OMIM
601591
Immunogen
Synthetic peptide of human PRKG2
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PRKG2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-PRKG2 antibody
WB: 1:200-1:1000
IHC: 1:25-1:100

Western Blot (WB) of anti-PRKG2 antibody

Western Blot analysis of Mouse brain and lung tissue using PRKG2 Polyclonal Antibody at dilution of 1:160
Rabbit Anti-PRKG2 Polyclonal Antibody – Cat# MBS2521199

Immunohistochemistry (IHC) of anti-PRKG2 antibody

Immunohistochemistry of paraffin-embedded Human liver cancer using PRKG2 Polyclonal Antibody at dilution of 1:20
Rabbit Anti-PRKG2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2521199

Immunohistochemistry (IHC) of anti-PRKG2 antibody

Immunohistochemistry of paraffin-embedded Human cervical cancer using PRKG2 Polyclonal Antibody at dilution of 1:20
Rabbit Anti-PRKG2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2521199

Other Notes

Small volumes of anti-PRKG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRKG2 purchase

MBS2521199 is an antibody targeting PRKG2. Also known as PRKG2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PRKG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
PRKG2 protein
NCBI Official Synonym Full Names
protein kinase, cGMP-dependent, type II
NCBI Official Symbol
PRKG2
NCBI Official Synonym Symbols
cGK2; cGKII; PRKGR2
UniProt Protein Name
cGMP-dependent protein kinase 2
UniProt Synonym Protein Names
cGMP-dependent protein kinase II; cGKII
UniProt Gene Name
PRKG2
UniProt Synonym Gene Names
PRKGR2; cGK 2; cGK2; cGKII
UniProt Entry Name
KGP2_HUMAN
NCBI Protein Information
cGMP-dependent protein kinase 2; cGMP-dependent protein kinase II

NCBI Summary for PRKG2

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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UniProt Comments for PRKG2

PKG2: an AGC kinase of the PKG family. Type II cGMP-dependent protein kinase is expressed at high levels in brain, lung and intestinal mucosa.

Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.12; Protein kinase, AGC; Kinase, protein; AGC group; PKG family

Chromosomal Location of Human Ortholog: 4q13.1-q21.1

Cellular Component: nuclear membrane; apical plasma membrane; cytosol

Molecular Function: protein homodimerization activity; cGMP-dependent protein kinase activity; cGMP binding; ATP binding; protein kinase activity

Biological Process: regulation of nitric-oxide synthase activity; circadian regulation of gene expression; blood coagulation; signal transduction; protein amino acid phosphorylation; nitric oxide metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PRKG2 antibody

 Reference Product  PubMed Publications
 SOX9 antibody  >6 publications with PRKG2 and SOX9
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