Rabbit Anti-FOXN1 Polyclonal Antibody – Cat# MBS2521847

Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using FOXN1 Polyclonal Antibody at dilution 1:15

FOXN1 Antibody – Rabbit Polyclonal

Name: FOXN1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2521847
Price: 160 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2521847

Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes… More details

$160 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FOXN1, Polyclonal Antibody

Full Product Name

FOXN1 Polyclonal Antibody

Product Gene Name

anti-FOXN1 antibody

Product Synonym Names

WHN, RONU, FKHL20

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Purity/Purification

Antigen affinity purification

Concentration

0.7mg/mL (lot specific)

Preparation and Storage

Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Molecular Weight

68,925 Da

OMIM

600838

Immunogen

Synthetic peptide of human FOXN1

Buffer

PBS with 0.05% sodium azide, 50% glycerol, pH7.3

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-FOXN1 antibody

ELISA (EIA), Immunohistochemistry (IHC)

Application Notes for anti-FOXN1 antibody

IHC: 1:25-1:100

Other Notes

Small volumes of anti-FOXN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FOXN1 purchase

MBS2521847 is an antibody targeting FOXN1. Also known as FOXN1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FOXN1. It may not necessarily be applicable to this product.

NCBI GI #

18201913

NCBI GeneID

8456

NCBI Accession #

NP_003584.2

UniProt Secondary Accession #

O15352; B2R9Q7

UniProt Related Accession #

O15353

GenBank Nucleotide #

NM_003593.2

NCBI Official Full Name

forkhead box protein N1

NCBI Official Synonym Full Names

forkhead box N1

NCBI Official Symbol

FOXN1

NCBI Official Synonym Symbols

WHN; RONU; FKHL20

UniProt Protein Name

Forkhead box protein N1

UniProt Synonym Protein Names

Winged-helix transcription factor nude

Protein Family

Forkhead box protein

UniProt Gene Name

FOXN1

UniProt Synonym Gene Names

RONU; WHN

UniProt Entry Name

FOXN1_HUMAN

NCBI Protein Information

forkhead box protein N1; Rowett nude; winged helix nude; winged-helix nude; winged-helix transcription factor nude

UniProt Comments for FOXN1

FOXN1: Transcriptional regulator involved in development. Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy (TIDAND). A disorder characterized by the association of congenital alopecia, severe T-cell immunodeficiency, and ridging and pitting of all nails.

Protein type: Cell development/differentiation; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; keratinocyte differentiation; epidermis development; organ morphogenesis; epithelial cell proliferation; hair follicle development; thymus development; regulation of T cell differentiation in the thymus; defense response; lymphocyte homeostasis

Disease: T-cell Immunodeficiency, Congenital Alopecia, And Nail Dystrophy

Research Articles on FOXN1

1. Identification of a unique mutation in FOXN1 that led to severe combined immunodeficiency in a female infant is reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FOXN1 antibody

Reference Product	PubMed Publications
AIRE antibody	>14 publications with FOXN1 and AIRE
GCM2 antibody	>10 publications with FOXN1 and GCM2
MSX2 antibody	>8 publications with FOXN1 and MSX2
CCL25 antibody	>4 publications with FOXN1 and CCL25
NOTCH1 antibody	>3 publications with FOXN1 and NOTCH1
WNT5B antibody	>2 publications with FOXN1 and WNT5B
FGFR3 antibody	>2 publications with FOXN1 and FGFR3
AKT1 antibody	>1 publications with FOXN1 and AKT1
DSC2 antibody	>1 publications with FOXN1 and DSC2

Diseases associated with anti-FOXN1 antibody

Disease Name	Pubmed Publications
Atrophy Antibodies	>6 publications with FOXN1 and Atrophy
Lung Neoplasms Antibodies	>5 publications with FOXN1 and Lung Neoplasms
Necrosis Antibodies	>5 publications with FOXN1 and Necrosis
Inflammation Antibodies	>4 publications with FOXN1 and Inflammation
Brain Diseases Antibodies	>4 publications with FOXN1 and Brain Diseases
Neoplasms, Experimental Antibodies	>3 publications with FOXN1 and Neoplasms, Experimental
Hyperplasia Antibodies	>3 publications with FOXN1 and Hyperplasia
Uterine Neoplasms Antibodies	>2 publications with FOXN1 and Uterine Neoplasms
Lymphoma Antibodies	>2 publications with FOXN1 and Lymphoma
Neoplasm Metastasis Antibodies	>2 publications with FOXN1 and Neoplasm Metastasis

Organs/Tissues associated with anti-FOXN1 antibody

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>111 publications with FOXN1 and Thymus
Mouth Antibodies	>2 publications with FOXN1 and Mouth
Larynx Antibodies	>1 publications with FOXN1 and Larynx