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DSC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2522225

The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DSC1, Polyclonal Antibody
Full Product Name
DSC1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
CDHF1; DG2/DG3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.7mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
93,835 Da
OMIM
125643
Immunogen
Synthetic peptide of human DSC1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DSC1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-DSC1 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-DSC1 antibody

Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using DSC1 Polyclonal Antibody at dilution 1:40
Rabbit Anti-DSC1 Polyclonal Antibody – Cat# MBS2522225

Immunohistochemistry (IHC) of anti-DSC1 antibody

Immunohistochemistry of paraffin-embedded Human brain tissue using DSC1 Polyclonal Antibody at dilution 1:40
Rabbit Anti-DSC1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2522225

Other Notes

Small volumes of anti-DSC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DSC1 purchase

MBS2522225 is an antibody targeting DSC1. Also known as DSC1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DSC1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
desmocollin-1 isoform Dsc1a preproprotein
NCBI Official Synonym Full Names
desmocollin 1
NCBI Official Symbol
DSC1
NCBI Official Synonym Symbols
CDHF1; DG2/DG3
UniProt Protein Name
Desmocollin-1
UniProt Synonym Protein Names
Cadherin family member 1; Desmosomal glycoprotein 2/3; DG2/DG3
Protein Family
UniProt Gene Name
DSC1
UniProt Synonym Gene Names
CDHF1; DG2/DG3
UniProt Entry Name
DSC1_HUMAN
NCBI Protein Information
desmocollin-1; cadherin family member 1; desmosomal glycoprotein 2/3

UniProt Comments for DSC1

DSC1: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q12.1

Cellular Component: desmosome; membrane; gap junction; integral to membrane; plasma membrane

Molecular Function: calcium ion binding

Biological Process: homophilic cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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