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SERPINB5 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2522239

Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene. [1] This protein belongs to the serpin (serine protease inhibitor) superfamily. [1] SERPINB5 also functions as a tumor suppressor… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SERPINB5, Polyclonal Antibody
Full Product Name
SERPINB5 Polyclonal Antibody
Product Gene Name
Product Synonym Names
PI5, maspin
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.05% sodium azide, 50% glycerol, pH7.4
Purity/Purification
Antigen purification
Concentration
2mg/mL (lot specific)
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight
42kDa
OMIM
154790
Immunogen
Recombinant protein of human SERPINB5
Note
Centrifuge before opening to ensure complete recovery of vial contents.

Product Categories/Family for anti-SERPINB5 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SERPINB5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-SERPINB5 antibody
WB: 1:1000 - 1:5000
IHC: 1:100 - 1:300

Western Blot (WB) of anti-SERPINB5 antibody

Western Blot analysis of Mouse esophagus and Human cervical cancer tissue using SERPINB5 Polyclonal Antibody at dilution of 1:1000
Rabbit Anti-SERPINB5 Polyclonal Antibody – Cat# MBS2522239

Immunohistochemistry (IHC) of anti-SERPINB5 antibody

Immunohistochemistry of paraffin-embedded Human esophagus cancer using SERPINB5 Polyclonal Antibody at dilution of 1:60
Rabbit Anti-SERPINB5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2522239

Immunohistochemistry (IHC) of anti-SERPINB5 antibody

Immunohistochemistry of paraffin-embedded Human lung cancer using SERPINB5 Polyclonal Antibody at dilution of 1:60
Rabbit Anti-SERPINB5 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2522239

Other Notes

Small volumes of anti-SERPINB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SERPINB5 purchase

MBS2522239 is an antibody targeting SERPINB5. Also known as SERPINB5 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINB5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
SERPINB5 protein
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade B (ovalbumin), member 5
NCBI Official Symbol
SERPINB5
NCBI Official Synonym Symbols
PI5; maspin
UniProt Protein Name
Serpin B5
UniProt Synonym Protein Names
Maspin; Peptidase inhibitor 5; PI-5
Protein Family
UniProt Gene Name
SERPINB5
UniProt Synonym Gene Names
PI5; PI-5
UniProt Entry Name
SPB5_HUMAN
NCBI Protein Information
serpin B5; PI-5; peptidase inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5

UniProt Comments for SERPINB5

maspin: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. Interacts with IRF6. Normal mammary epithelial cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.33

Cellular Component: extracellular space; cytoplasm

Molecular Function: serine-type endopeptidase inhibitor activity; protein binding

Biological Process: extracellular matrix organization and biogenesis; morphogenesis of an epithelium; cell motility; regulation of epithelial cell proliferation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SERPINB5 antibody

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