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MTUS1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2523488

This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
MTUS1, Polyclonal Antibody
Full Product Name
MTUS1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
ATBP; ATIP; ICIS; MP44; MTSG1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
0.9mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
48,050 Da
OMIM
114550
Immunogen
Recombinant protein of human MTUS1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MTUS1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-MTUS1 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-MTUS1 antibody

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MTUS1 Polyclonal Antibody at dilution 1:20
Rabbit Anti-MTUS1 Polyclonal Antibody – Cat# MBS2523488

Immunohistochemistry (IHC) of anti-MTUS1 antibody

Immunohistochemistry of paraffin-embedded Human brain tissue using MTUS1 Polyclonal Antibody at dilution 1:20
Rabbit Anti-MTUS1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2523488

Other Notes

Small volumes of anti-MTUS1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MTUS1 purchase

MBS2523488 is an antibody targeting MTUS1. Also known as MTUS1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MTUS1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
microtubule-associated tumor suppressor 1 isoform 6
NCBI Official Synonym Full Names
microtubule associated tumor suppressor 1
NCBI Official Symbol
MTUS1
NCBI Official Synonym Symbols
ATBP; ATIP; ICIS; MP44; MTSG1
UniProt Protein Name
Microtubule-associated tumor suppressor 1
UniProt Synonym Protein Names
AT2 receptor-binding protein; Angiotensin-II type 2 receptor-interacting protein; Mitochondrial tumor suppressor 1
UniProt Gene Name
MTUS1
UniProt Synonym Gene Names
ATBP; ATIP; GK1; KIAA1288; MTSG1
UniProt Entry Name
MTUS1_HUMAN
NCBI Protein Information
microtubule-associated tumor suppressor 1; AT2 receptor-binding protein; AT2 receptor-interacting protein; AT2R binding protein; angiotensin-II type 2 receptor-interacting protein; erythroid differentiation-related; mitochondrial tumor suppressor gene 1; transcription factor MTSG1

NCBI Summary for MTUS1

This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
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UniProt Comments for MTUS1

MTUS1: Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. Defects in MTUS1 may be a cause of hepatocellular carcinoma (HCC). Belongs to the MTUS1 family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; Tumor suppressor

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: Golgi apparatus; microtubule; extracellular space; mitochondrion; plasma membrane; microtubule organizing center; spindle; nucleus
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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