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EPS15L1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2523882

Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of… More details

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Product Overview

Online Datasheet in PDF
Product Name
EPS15L1, Polyclonal Antibody
Full Product Name
EPS15L1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
EPS15R
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.4mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
66,479 Da
Immunogen
Recombinant protein of human EPS15L1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-EPS15L1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-EPS15L1 antibody
WB: 1:500-1:2000
IHC: 1:25-1:100

Western Blot (WB) of anti-EPS15L1 antibody

Western Blot analysis of Hela, PC3, 231 and 293T cell using EPS15L1 Polyclonal Antibody at dilution of 1:350
Rabbit Anti-EPS15L1 Polyclonal Antibody – Cat# MBS2523882

Immunohistochemistry (IHC) of anti-EPS15L1 antibody

Immunohistochemistry of paraffin-embedded Human thyroid cancer using EPS15L1 Polyclonal Antibody at dilution of 1:30
Rabbit Anti-EPS15L1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2523882

Immunohistochemistry (IHC) of anti-EPS15L1 antibody

Immunohistochemistry of paraffin-embedded Human colon cancer using EPS15L1 Polyclonal Antibody at dilution of 1:30
Rabbit Anti-EPS15L1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2523882

Other Notes

Small volumes of anti-EPS15L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPS15L1 purchase

MBS2523882 is an antibody targeting EPS15L1. Also known as EPS15L1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EPS15L1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
EPS15L1 protein, partial
NCBI Official Synonym Full Names
epidermal growth factor receptor pathway substrate 15-like 1
NCBI Official Symbol
EPS15L1
NCBI Official Synonym Symbols
EPS15R
UniProt Protein Name
Epidermal growth factor receptor substrate 15-like 1
UniProt Synonym Protein Names
Eps15-related protein; Eps15R
UniProt Gene Name
EPS15L1
UniProt Synonym Gene Names
EPS15R; Eps15R
UniProt Entry Name
EP15R_HUMAN
NCBI Protein Information
epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; eps15-related protein

UniProt Comments for EPS15L1

EPS15R: epidermal growth factor receptor substrate protein 15R. Contains three EH domains which are implicated in endocytosis, vesicle transport and signal transduction. All three EH domains contain calcium-binding domains ofthe EF-hand type. Contains 2 UIM motifs, which are is responsible for ubiquitin recognition and monoubiquitination. May function as an adaptor between ubiquitinated proteins and the clathrin coat or other endocytic scaffolds.

Protein type: Vesicle; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: membrane; plasma membrane; coated pit; nucleus

Molecular Function: protein binding; calcium ion binding

Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; endocytosis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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