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PLAUR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2524126

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PLAUR, Polyclonal Antibody
Full Product Name
PLAUR Polyclonal Antibody
Product Gene Name
anti-PLAUR antibody
Product Synonym Names
CD87; UPAR; URKR; U-PAR
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
PBS with 0.05% sodium azide, 50% glycerol, pH7.4
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
37kDa
OMIM
173391
3D Structure
ModBase 3D Structure for Q03405
Immunogen
Recombinant protein of human PLAUR
Note
Centrifuge before opening to ensure complete recovery of vial contents.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PLAUR antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-PLAUR antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-PLAUR antibody

Western Blot analysis of A549 cell using PLAUR Polyclonal Antibody at dilution of 1:450
Rabbit Anti-PLAUR Polyclonal Antibody – Cat# MBS2524126

Immunohistochemistry (IHC) of anti-PLAUR antibody

Immunohistochemistry of paraffin-embedded Human lung cancer using PLAUR Polyclonal Antibody at dilution of 1:60
Rabbit Anti-PLAUR Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2524126

Immunohistochemistry (IHC) of anti-PLAUR antibody

Immunohistochemistry of paraffin-embedded Human cervical cancer using PLAUR Polyclonal Antibody at dilution of 1:60
Rabbit Anti-PLAUR Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2524126

Other Notes

Small volumes of anti-PLAUR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLAUR purchase

MBS2524126 is an antibody targeting PLAUR. Also known as PLAUR Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLAUR. It may not necessarily be applicable to this product.

NCBI GI #
48146021
NCBI GeneID
5329
UniProt Primary Accession #
Q03405
UniProt Secondary Accession #
Q12876; Q15845; Q16887; Q6IB52; Q9BWT0; Q9NYC8; Q9UD69; Q9UEA6; Q9UM92; Q9UMV0; A8K409
UniProt Related Accession #
Q03405
NCBI Official Full Name
PLAUR
NCBI Official Synonym Full Names
plasminogen activator, urokinase receptor
NCBI Official Symbol
PLAUR
NCBI Official Synonym Symbols
CD87; UPAR; URKR; U-PAR
UniProt Protein Name
Urokinase plasminogen activator surface receptor
UniProt Synonym Protein Names
Monocyte activation antigen Mo3; CD_antigen: CD87
Protein Family
Urokinase plasminogen activator surface receptor
UniProt Gene Name
PLAUR
UniProt Synonym Gene Names
MO3; UPAR; U-PAR; uPAR
UniProt Entry Name
UPAR_HUMAN
NCBI Protein Information
urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; urokinase-type plasminogen activator (uPA) receptor

UniProt Comments for PLAUR

uPAR: Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. Monomer (Probable). Interacts with MRC2. Interacts (via the UPAR/Ly6 domains) with SRPX2. Expressed in neurons of the rolandic area of the brain. Expressed in the brain. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, GPI anchor; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: endoplasmic reticulum membrane; focal adhesion; extrinsic to membrane; integral to plasma membrane; endoplasmic reticulum lumen; plasma membrane; integral to membrane

Molecular Function: protein domain specific binding; protein binding; U-plasminogen activator receptor activity; enzyme binding; receptor activity; receptor binding

Biological Process: fibrinolysis; cellular protein metabolic process; attachment of GPI anchor to protein; regulation of proteolysis; C-terminal protein lipidation; blood coagulation; post-translational protein modification; signal transduction; cell motility; chemotaxis
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Research Articles on PLAUR

1. Soluble urokinase plasminogen activator receptor is a sensitive and specific independent predictive biomarkers in preterm babies with bronchopulmonary dysplasia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PLAUR antibody

 Products by Pathway  Pathway Diagram
 Arf6 Downstream Pathway antibodies  Arf6 Downstream Pathway Diagram
 Attachment Of GPI Anchor To UPAR Pathway antibodies  Attachment Of GPI Anchor To UPAR Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Dissolution Of Fibrin Clot Pathway antibodies  Dissolution Of Fibrin Clot Pathway Diagram
 FGF Signaling Pathway antibodies  FGF Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway antibodies  Post-translational Modification: Synthesis Of GPI-anchored Proteins Pathway Diagram

Diseases associated with anti-PLAUR antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >314 publications with PLAUR and Carcinoma
 Neoplasm Invasiveness Antibodies  >262 publications with PLAUR and Neoplasm Invasiveness
 Neoplasm Metastasis Antibodies  >240 publications with PLAUR and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >165 publications with PLAUR and Breast Neoplasms
 Inflammation Antibodies  >115 publications with PLAUR and Inflammation
 Lung Diseases Antibodies  >91 publications with PLAUR and Lung Diseases
 Cardiovascular Diseases Antibodies  >83 publications with PLAUR and Cardiovascular Diseases
 Lung Neoplasms Antibodies  >76 publications with PLAUR and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >75 publications with PLAUR and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >68 publications with PLAUR and Disease Models, Animal

Organs/Tissues associated with anti-PLAUR antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >507 publications with PLAUR and Blood
 Vascular Antibodies  >303 publications with PLAUR and Vascular
 Lung Antibodies  >148 publications with PLAUR and Lung
 Muscle Antibodies  >98 publications with PLAUR and Muscle
 Brain Antibodies  >86 publications with PLAUR and Brain
 Liver Antibodies  >83 publications with PLAUR and Liver
 Bone Antibodies  >81 publications with PLAUR and Bone
 Embryonic Tissue Antibodies  >80 publications with PLAUR and Embryonic Tissue
 Kidney Antibodies  >77 publications with PLAUR and Kidney
 Skin Antibodies  >68 publications with PLAUR and Skin
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