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PRDX4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2525708

The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRDX4, Polyclonal Antibody
Full Product Name
PRDX4 Antibody
Product Gene Name
Product Synonym Names
AOE37-2;AOE372;HEL-S-97n;PRX-4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.02% sodium azide and 50% glycerol pH 7.4
Purity/Purification
Affinity purification
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20°C. Avoid freeze / thaw cycles.
Molecular Weight
Calculated MW 30kDa
Observed MW 28kDa
OMIM
300927
Immunogen
Recombinant protein of human PRDX4
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-23974
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PRDX4 antibody
Western Blot (WB)
Application Notes for anti-PRDX4 antibody
WB 1:500 - 1:2000

Western Blot (WB) of anti-PRDX4 antibody

Western blot analysis of extracts of various cell lines, using PRDX4 antibody.
Rabbit Anti-PRDX4 Polyclonal Antibody – Cat# MBS2525708

Immunohistochemistry (IHC) of anti-PRDX4 antibody

Immunohistochemistry of paraffin-embedded human kidney cancer using PRDX4 antibody at dilution of 1:200 (x400 lens)
Rabbit Anti-PRDX4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2525708

Immunohistochemistry (IHC) of anti-PRDX4 antibody

Immunohistochemistry of paraffin-embedded human stomach using PRDX4 antibody at dilution of 1:200 (x400 lens)
Rabbit Anti-PRDX4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2525708

Other Notes

Small volumes of anti-PRDX4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRDX4 purchase

MBS2525708 is an antibody targeting PRDX4. Also known as PRDX4 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PRDX4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peroxiredoxin-4
NCBI Official Synonym Full Names
peroxiredoxin 4
NCBI Official Symbol
PRDX4
NCBI Official Synonym Symbols
PRX-4; AOE372; AOE37-2; HEL-S-97n
UniProt Protein Name
Peroxiredoxin-4
UniProt Synonym Protein Names
Antioxidant enzyme AOE372; AOE37-2; Peroxiredoxin IV; Prx-IV; Thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372
Protein Family
UniProt Gene Name
PRDX4
UniProt Synonym Gene Names
AOE37-2; Prx-IV
UniProt Entry Name
PRDX4_HUMAN
NCBI Protein Information
peroxiredoxin-4; antioxidant enzyme AOE372; epididymis secretory sperm binding protein Li 97n; peroxiredoxin IV; prx-IV; thioredoxin peroxidase (antioxidant enzyme); thioredoxin peroxidase AO372; thioredoxin-dependent peroxide reductase A0372

UniProt Comments for PRDX4

PRDX4: Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Belongs to the AhpC/TSA family.

Protein type: EC 1.11.1.15; Oxidoreductase; Secreted; Secreted, signal peptide; Mitochondrial

Chromosomal Location of Human Ortholog: Xp22.11

Cellular Component: extracellular space; smooth endoplasmic reticulum; mitochondrion; cytosol; nucleus

Molecular Function: protein binding; protein homodimerization activity; thioredoxin peroxidase activity

Biological Process: extracellular matrix organization and biogenesis; protein maturation via protein folding; 4-hydroxyproline metabolic process; cell redox homeostasis; male gonad development; spermatogenesis; I-kappaB phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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Pathways associated with anti-PRDX4 antibody

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