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MAGEC2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2525907

This gene is a member of the MAGEC gene family. It is not expressed in normal tissues, except for testis, and is expressed in tumors of various histological types. This gene and the other MAGEC genes are clustered on chromosome Xq26-q27. More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MAGEC2, Polyclonal Antibody
Full Product Name
MAGEC2 Polyclonal Antibody
Product Gene Name
Product Synonym Names
CT10; HCA587; MAGEE1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.6mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
41,163 Da
OMIM
300468
Immunogen
Synthetic peptide of human MAGEC2
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Product Categories/Family for anti-MAGEC2 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MAGEC2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-MAGEC2 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-MAGEC2 antibody

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MAGEC2 Polyclonal Antibody at dilution 1:40
Rabbit Anti-MAGEC2 Polyclonal Antibody – Cat# MBS2525907

Immunohistochemistry (IHC) of anti-MAGEC2 antibody

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MAGEC2 Polyclonal Antibody at dilution 1:40
Rabbit Anti-MAGEC2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2525907

Other Notes

Small volumes of anti-MAGEC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MAGEC2 purchase

MBS2525907 is an antibody targeting MAGEC2. Also known as MAGEC2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MAGEC2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
melanoma-associated antigen C2
NCBI Official Synonym Full Names
melanoma antigen family C2
NCBI Official Symbol
MAGEC2
NCBI Official Synonym Symbols
CT10; HCA587; MAGEE1
UniProt Protein Name
Melanoma-associated antigen C2
UniProt Synonym Protein Names
Cancer/testis antigen 10; CT10; Hepatocellular carcinoma-associated antigen 587; MAGE-C2 antigen; MAGE-E1 antigen
UniProt Gene Name
MAGEC2
UniProt Synonym Gene Names
HCA587; MAGEE1; CT10
UniProt Entry Name
MAGC2_HUMAN
NCBI Protein Information
melanoma-associated antigen C2; MAGE-C2 antigen; MAGE-E1 antigen; cancer/testis antigen 10; hepatocellular cancer antigen 587; hepatocellular carcinoma-associated antigen 587; melanoma antigen family C, 2; melanoma antigen, family E, 1, cancer/testis specific

UniProt Comments for MAGEC2

MAGE-C2: Proposed to enhance ubiquitin ligase activity of RING- type zinc finger-containing E3 ubiquitin-protein ligases. In vitro enhances ubiquitin ligase activity of TRIM28 and stimulates p53/TP53 ubiquitination in presence of Ubl-conjugating enzyme UBE2H leading to p53/TP53 degradation. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzymes (E2) at the E3:substrate complex.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: Xq27

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; ubiquitin protein ligase binding

Biological Process: cellular protein catabolic process; positive regulation of ubiquitin-protein ligase activity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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