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TNFSF13B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2526248

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and… More details

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Product Overview

Online Datasheet in PDF
Product Name
TNFSF13B, Polyclonal Antibody
Full Product Name
TNFSF13B Polyclonal Antibody
Product Gene Name
anti-TNFSF13B antibody
Product Synonym Names
DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.2mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
17,578 Da
OMIM
603969
3D Structure
ModBase 3D Structure for Q6FHD6
Immunogen
Recombinant protein of human TNFSF13B
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Product Categories/Family for anti-TNFSF13B antibody

Cancer; Cell biology
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TNFSF13B antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-TNFSF13B antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-TNFSF13B antibody

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TNFSF13B Polyclonal Antibody at dilution 1:30
Rabbit Anti-TNFSF13B Polyclonal Antibody – Cat# MBS2526248

Immunohistochemistry (IHC) of anti-TNFSF13B antibody

Immunohistochemistry of paraffin-embedded Human lymphoma tissue using TNFSF13B Polyclonal Antibody at dilution 1:30
Rabbit Anti-TNFSF13B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2526248

Other Notes

Small volumes of anti-TNFSF13B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TNFSF13B purchase

MBS2526248 is an antibody targeting TNFSF13B. Also known as TNFSF13B Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TNFSF13B. It may not necessarily be applicable to this product.

NCBI GI #
49456593
NCBI GeneID
10673
NCBI Accession #
CAG46617.1
UniProt Primary Accession #
Q6FHD6
UniProt Secondary Accession #
Q6FHD6; Q7Z5J2; E0ADT7
UniProt Related Accession #
Q9Y275
NCBI Official Full Name
TNFSF13B
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 13b
NCBI Official Symbol
TNFSF13B
NCBI Official Synonym Symbols
DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNFSF20
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 13B
UniProt Synonym Protein Names
B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD_antigen: CD257Cleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form
Protein Family
Tumor necrosis factor ligand superfamily
UniProt Gene Name
TNFSF13B
UniProt Synonym Gene Names
BAFF; BLYS; TALL1; TNFSF20; ZTNF4; BLyS; TALL-1
UniProt Entry Name
TN13B_HUMAN
NCBI Protein Information
tumor necrosis factor ligand superfamily member 13B; ApoL related ligand TALL-1; B-cell-activating factor; B-lymphocyte stimulator; Delta4 BAFF; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; delta BAFF; dendritic cell-derived TNF-like molecule; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor-like protein ZTNF4

UniProt Comments for TNFSF13B

BAFF: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Apoptosis; Cytokine; Cell cycle regulation

Chromosomal Location of Human Ortholog: 13q32-q34

Cellular Component: extracellular space; perinuclear region of cytoplasm; cytoplasm; integral to membrane; plasma membrane

Molecular Function: protein binding; cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: cell proliferation; B cell costimulation; B cell homeostasis; immunoglobulin secretion; T cell costimulation; positive regulation of cell proliferation; positive regulation of germinal center formation; positive regulation of B cell proliferation; immune response; positive regulation of T cell proliferation; signal transduction
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Research Articles on TNFSF13B

1. Availability of BAFF determines BAFF-R and TACI expression on B cells in common variable immunodeficiency.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TNFSF13B antibody

 Reference Product  PubMed Publications
 TNFRSF13C antibody  >121 publications with TNFSF13B and TNFRSF13C
 TNFRSF17 antibody  >104 publications with TNFSF13B and TNFRSF17
 TNFRSF13B antibody  >78 publications with TNFSF13B and TNFRSF13B
 IL6 antibody  >14 publications with TNFSF13B and IL6
 AICDA antibody  >6 publications with TNFSF13B and AICDA
 IFNG antibody  >2 publications with TNFSF13B and IFNG
 CD40LG antibody  >1 publications with TNFSF13B and CD40LG

Pathways associated with anti-TNFSF13B antibody

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 Intestinal Immune Network For IgA Production Pathway antibodies  Intestinal Immune Network For IgA Production Pathway Diagram
 NF-kappa B Signaling Pathway antibodies  NF-kappa B Signaling Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Rheumatoid Arthritis Pathway antibodies  Rheumatoid Arthritis Pathway Diagram
 Spinal Cord Injury Pathway antibodies  Spinal Cord Injury Pathway Diagram

Diseases associated with anti-TNFSF13B antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >451 publications with TNFSF13B and Necrosis
 Inflammation Antibodies  >77 publications with TNFSF13B and Inflammation
 Nervous System Diseases Antibodies  >54 publications with TNFSF13B and Nervous System Diseases
 Kidney Diseases Antibodies  >31 publications with TNFSF13B and Kidney Diseases
 Skin Diseases Antibodies  >25 publications with TNFSF13B and Skin Diseases
 Liver Diseases Antibodies  >14 publications with TNFSF13B and Liver Diseases
 Bone Marrow Diseases Antibodies  >13 publications with TNFSF13B and Bone Marrow Diseases
 Thrombocytopenia Antibodies  >12 publications with TNFSF13B and Thrombocytopenia
 Hyperplasia Antibodies  >10 publications with TNFSF13B and Hyperplasia
 Leukopenia Antibodies  >8 publications with TNFSF13B and Leukopenia

Organs/Tissues associated with anti-TNFSF13B antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >605 publications with TNFSF13B and Blood
 Bone Marrow Antibodies  >69 publications with TNFSF13B and Bone Marrow
 Lymph Node Antibodies  >46 publications with TNFSF13B and Lymph Node
 Kidney Antibodies  >36 publications with TNFSF13B and Kidney
 Skin Antibodies  >18 publications with TNFSF13B and Skin
 Vascular Antibodies  >14 publications with TNFSF13B and Vascular
 Liver Antibodies  >13 publications with TNFSF13B and Liver
 Brain Antibodies  >13 publications with TNFSF13B and Brain
 Thymus Antibodies  >8 publications with TNFSF13B and Thymus
 Pharynx Antibodies  >8 publications with TNFSF13B and Pharynx
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