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MGLL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2526932

This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MGLL, Polyclonal Antibody
Full Product Name
MGLL Polyclonal Antibody
Product Gene Name
anti-MGLL antibody
Product Synonym Names
MGL; HUK5; MAGL; HU-K5
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.5mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
31,149 Da
OMIM
609699
Immunogen
Synthetic peptide of human MGLL
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Product Categories/Family for anti-MGLL antibody

Cancer
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MGLL antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-MGLL antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-MGLL antibody

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MGLL Polyclonal Antibody at dilution 1:40
Rabbit Anti-MGLL Polyclonal Antibody – Cat# MBS2526932

Immunohistochemistry (IHC) of anti-MGLL antibody

Immunohistochemistry of paraffin-embedded Human brain tissue using MGLL Polyclonal Antibody at dilution 1:40
Rabbit Anti-MGLL Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2526932

Other Notes

Small volumes of anti-MGLL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MGLL purchase

MBS2526932 is an antibody targeting MGLL. Also known as MGLL Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MGLL. It may not necessarily be applicable to this product.

NCBI GI #
48145787
NCBI GeneID
11343
NCBI Accession #
CAG33116.1
UniProt Secondary Accession #
Q6IBG9; Q96AA5; B3KRC2; B7Z9D1
UniProt Related Accession #
Q99685
NCBI Official Full Name
MGLL
NCBI Official Synonym Full Names
monoglyceride lipase
NCBI Official Symbol
MGLL
NCBI Official Synonym Symbols
MGL; HUK5; MAGL; HU-K5
UniProt Protein Name
Monoglyceride lipase
UniProt Synonym Protein Names
HU-K5; Lysophospholipase homolog; Lysophospholipase-like; Monoacylglycerol lipase; MAGL
Protein Family
Monoglyceride lipase
UniProt Gene Name
MGLL
UniProt Synonym Gene Names
MGL; MAGL
UniProt Entry Name
MGLL_HUMAN
NCBI Protein Information
monoglyceride lipase; lysophospholipase homolog; monoacylglycerol lipase

UniProt Comments for MGLL

MGLL: Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. Belongs to the AB hydrolase superfamily. Monoacylglycerol lipase family.

Protein type: EC 3.1.1.23; Lipid Metabolism - glycerolipid; Phospholipase

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: nucleoplasm; endoplasmic reticulum membrane; extrinsic to membrane; plasma membrane; synapse; cytosol

Molecular Function: protein homodimerization activity; acylglycerol lipase activity; lipid binding; lysophospholipase activity

Biological Process: platelet activation; glycerophospholipid biosynthetic process; regulation of signal transduction; regulation of axon extension; phospholipid metabolic process; triacylglycerol catabolic process; regulation of inflammatory response; arachidonic acid metabolic process; regulation of sensory perception of pain; lipid metabolic process; blood coagulation; inflammatory response; fatty acid biosynthetic process; acylglycerol catabolic process
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Research Articles on MGLL

1. In subcutaneous adipose tissue, DAGL-a mRNA was upregulated and fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mRNAs were down-regulated in obese subjects, but the diets had no influence.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MGLL antibody

 Reference Product  PubMed Publications
 PNPLA2 antibody  >3 publications with MGLL and PNPLA2
 LIPE antibody  >3 publications with MGLL and LIPE
 LPL antibody  >1 publications with MGLL and LPL

Pathways associated with anti-MGLL antibody

 Products by Pathway  Pathway Diagram
 Acyl Chain Remodeling Of DAG And TAG Pathway antibodies  Acyl Chain Remodeling Of DAG And TAG Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Arachidonate Production From DAG Pathway antibodies  Arachidonate Production From DAG Pathway Diagram
 Effects Of PIP2 Hydrolysis Pathway antibodies  Effects Of PIP2 Hydrolysis Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram

Diseases associated with anti-MGLL antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with MGLL and Inflammation
 Disease Models, Animal Antibodies  >3 publications with MGLL and Disease Models, Animal
 Fatty Liver Antibodies  >3 publications with MGLL and Fatty Liver
 Breast Neoplasms Antibodies  >2 publications with MGLL and Breast Neoplasms
 Liver Diseases Antibodies  >2 publications with MGLL and Liver Diseases
 Cardiovascular Diseases Antibodies  >1 publications with MGLL and Cardiovascular Diseases
 Weight Gain Antibodies  >1 publications with MGLL and Weight Gain
 Weight Loss Antibodies  >1 publications with MGLL and Weight Loss
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with MGLL and Prenatal Exposure Delayed Effects
 Necrosis Antibodies  >1 publications with MGLL and Necrosis

Organs/Tissues associated with anti-MGLL antibody

 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >5 publications with MGLL and Adipose Tissue
 Blood Antibodies  >5 publications with MGLL and Blood
 Liver Antibodies  >4 publications with MGLL and Liver
 Muscle Antibodies  >3 publications with MGLL and Muscle
 Intestine Antibodies  >3 publications with MGLL and Intestine
 Connective Tissue Antibodies  >2 publications with MGLL and Connective Tissue
 Brain Antibodies  >2 publications with MGLL and Brain
 Vascular Antibodies  >1 publications with MGLL and Vascular
 Skin Antibodies  >1 publications with MGLL and Skin
 Pancreas Antibodies  >1 publications with MGLL and Pancreas
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