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BNIP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2526995

This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BNIP1, Polyclonal Antibody
Full Product Name
BNIP1 Polyclonal Antibody
Product Gene Name
anti-BNIP1 antibody
Product Synonym Names
NIP1; SEC20; TRG-8
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
27,333 Da
OMIM
603291
Immunogen
Recombinant protein of human BNIP1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Product Categories/Family for anti-BNIP1 antibody

Cell Biology
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-BNIP1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-BNIP1 antibody
WB: 1:200-1:1000
IHC: 1:25-1:100

Western Blot (WB) of anti-BNIP1 antibody

Western Blot analysis of Jurkat and A172 cell, Human liver cancer tissue using BNIP1 Polyclonal Antibody at dilution of 1:275
Rabbit Anti-BNIP1 Polyclonal Antibody – Cat# MBS2526995

Immunohistochemistry (IHC) of anti-BNIP1 antibody

Immunohistochemistry of paraffin-embedded Human esophagus cancer using BNIP1 Polyclonal Antibody at dilution of 1:30
Rabbit Anti-BNIP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2526995

Immunohistochemistry (IHC) of anti-BNIP1 antibody

Immunohistochemistry of paraffin-embedded Human thyroid cancer using BNIP1 Polyclonal Antibody at dilution of 1:30
Rabbit Anti-BNIP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2526995

Other Notes

Small volumes of anti-BNIP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BNIP1 purchase

MBS2526995 is an antibody targeting BNIP1. Also known as BNIP1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BNIP1. It may not necessarily be applicable to this product.

NCBI GI #
558842
NCBI GeneID
662
NCBI Accession #
AAC00020.1
UniProt Secondary Accession #
O75622; O75623; O75624; Q6K044; Q96FG4; D3DQM3; D3DQM4; D3DQM5; D3DQM6
UniProt Related Accession #
Q12981
NCBI Official Full Name
BCL2/adenovirus E1B 19kD-interacting protein 1
NCBI Official Synonym Full Names
BCL2/adenovirus E1B 19kDa interacting protein 1
NCBI Official Symbol
BNIP1
NCBI Official Synonym Symbols
NIP1; SEC20; TRG-8
UniProt Protein Name
Vesicle transport protein SEC20
UniProt Synonym Protein Names
BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; Transformation-related gene 8 protein; TRG-8
Protein Family
Vesicle transport protein
UniProt Gene Name
BNIP1
UniProt Synonym Gene Names
NIP1; SEC20L; TRG-8
UniProt Entry Name
SEC20_HUMAN
NCBI Protein Information
vesicle transport protein SEC20; BCL2/adenovirus E1B 19 kDa protein-interacting protein 1; transformation-related gene 8 protein

UniProt Comments for BNIP1

BNIP1: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. Belongs to the SEC20 family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q33-q34

Cellular Component: SNARE complex; intracellular membrane-bound organelle; mitochondrion; endoplasmic reticulum; cytoplasm; integral to endoplasmic reticulum membrane; nuclear envelope

Molecular Function: SNAP receptor activity; protein binding

Biological Process: vesicle-mediated transport; endoplasmic reticulum membrane fusion; endoplasmic reticulum organization and biogenesis; apoptosis; autophagy; negative regulation of apoptosis
Show more

Research Articles on BNIP1

1. BNip1 functions as a downstream modulator of RNF186 to direct endoplasmic reticulum stress-associated apoptotic signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BNIP1 antibody

 Reference Product  PubMed Publications
 BCL2 antibody  >3 publications with BNIP1 and BCL2
 SEC22B antibody  >2 publications with BNIP1 and SEC22B
 USE1 antibody  >2 publications with BNIP1 and USE1
 RNF185 antibody  >1 publications with BNIP1 and RNF185

Pathways associated with anti-BNIP1 antibody

 Products by Pathway  Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram
 SNARE Interactions In Vesicular Transport Pathway antibodies  SNARE Interactions In Vesicular Transport Pathway Diagram

Diseases associated with anti-BNIP1 antibody

 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >2 publications with BNIP1 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >2 publications with BNIP1 and Liver Diseases
 Heart Diseases Antibodies  >2 publications with BNIP1 and Heart Diseases
 Necrosis Antibodies  >2 publications with BNIP1 and Necrosis
 Hypertension Antibodies  >1 publications with BNIP1 and Hypertension
 Cardiomyopathies Antibodies  >1 publications with BNIP1 and Cardiomyopathies
 Kidney Diseases Antibodies  >1 publications with BNIP1 and Kidney Diseases
 Hypertrophy Antibodies  >1 publications with BNIP1 and Hypertrophy

Organs/Tissues associated with anti-BNIP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >5 publications with BNIP1 and Muscle
 Heart Antibodies  >3 publications with BNIP1 and Heart
 Brain Antibodies  >3 publications with BNIP1 and Brain
 Liver Antibodies  >3 publications with BNIP1 and Liver
 Lymph Antibodies  >1 publications with BNIP1 and Lymph
 Kidney Antibodies  >1 publications with BNIP1 and Kidney
 Lymph Node Antibodies  >1 publications with BNIP1 and Lymph Node
 Eye Antibodies  >1 publications with BNIP1 and Eye
 Blood Antibodies  >1 publications with BNIP1 and Blood
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