Transcription Factor 20 (TCF20) ELISA Kit for Sheep

Name: Sheep TCF20 ELISA Kit; Transcription Factor 20; MyBioSource
Brand: MyBioSource
SKU: MBS025270
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS025270

MBS025270 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transcription Factor 20 (TCF20) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Transcription Factor 20 (TCF20), ELISA Kit

Full Product Name

Sheep Transcription Factor 20 ELISA Kit

Product Gene Name

TCF20 elisa kit

Species Reactivity

Sheep

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

211,771 Da

Chromosome Location

Chromosome: 22; NC_000022.10 (42556019..42611445, complement). Location: 22q13.3; 22q13.3

OMIM

603107

3D Structure

ModBase 3D Structure for Q9UGU0

Other Notes

Small volumes of TCF20 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TCF20. It may not necessarily be applicable to this product.

NCBI GI #

31652244

NCBI GeneID

6942

NCBI Accession #

NP_005641.1

UniProt Primary Accession #

Q9UGU0

UniProt Secondary Accession #

O14528; Q13078; Q4V353; Q9H4M0; A9JX12

UniProt Related Accession #

Q9UGU0

GenBank Nucleotide #

NM_005650.2

NCBI Official Full Name

transcription factor 20 isoform 1

NCBI Official Synonym Full Names

transcription factor 20 (AR1)

NCBI Official Symbol

TCF20

NCBI Official Synonym Symbols

AR1; SPBP; TCF-20

UniProt Protein Name

Transcription factor 20

UniProt Synonym Protein Names

Nuclear factor SPBP; Protein AR1; Stromelysin-1 PDGF-responsive element-binding protein

Protein Family

Transcription factor

UniProt Gene Name

TCF20

UniProt Synonym Gene Names

KIAA0292; SPBP; TCF-20

UniProt Entry Name

TCF20_HUMAN

NCBI Protein Information

transcription factor 20; nuclear factor SPBP; SPRE-binding protein; stromelysin-1 PDGF-responsive element-binding protein; stromelysin-1 platelet-derived growth factor-responsive element binding protein

NCBI Summary for TCF20

This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

UniProt Comments for TCF20

TCF20: a transcriptional activator. Binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator. Two alternatively spliced isoforms have been described. Isoform 1 is exclusively expressed in brain, heart and testis, and predominates in liver and kidney. Isoform 2 predominates in lung.

Protein type: DNA-binding; Nuclear receptor co-regulator; Transcription factor

Chromosomal Location of Human Ortholog: 22q13.3|22q13.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: DNA binding; zinc ion binding; transcription coactivator activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on TCF20

1. Study has identified SPBP as a transcriptional coactivator of AR. We also show that Pax6 inhibits SPBP-mediated enhancement of AR activity on the AR target gene probasin promoter, a repression that was partly reversed by increased expression of SPBP.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TCF20 elisa kit

Reference Product	PubMed Publications
MMP3 elisa kit	>1 publications with TCF20 and MMP3
RNF4 elisa kit	>1 publications with TCF20 and RNF4
JUN elisa kit	>1 publications with TCF20 and JUN
TOPBP1 elisa kit	>1 publications with TCF20 and TOPBP1

Pathways associated with TCF20 elisa kit

Products by Pathway	Pathway Diagram
Matrix Metalloproteinases Pathway antibodies	Matrix Metalloproteinases Pathway Diagram

Diseases associated with TCF20 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3 publications with TCF20 and Neoplasms
Fibrosis Antibodies	>1 publications with TCF20 and Fibrosis
Inflammation Antibodies	>1 publications with TCF20 and Inflammation
Necrosis Antibodies	>1 publications with TCF20 and Necrosis

Organs/Tissues associated with TCF20 elisa kit

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>2 publications with TCF20 and Prostate
Eye Antibodies	>1 publications with TCF20 and Eye
Ovary Antibodies	>1 publications with TCF20 and Ovary
Lung Antibodies	>1 publications with TCF20 and Lung