• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

AGFG1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2527227

The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AGFG1, Polyclonal Antibody
Full Product Name
AGFG1 Polyclonal Antibody
Product Gene Name
anti-AGFG1 antibody
Product Synonym Names
HRB; RAB; RIP
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
2.2mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
60,767 Da
OMIM
600862
Immunogen
Recombinant protein of human AGFG1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-AGFG1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-AGFG1 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-AGFG1 antibody

Western Blot analysis of A172, Hela and 293T cell, K562 cell and Human testis tissue using AGFG1 Polyclonal Antibody at dilution of 1:533
Rabbit Anti-AGFG1 Polyclonal Antibody – Cat# MBS2527227

Immunohistochemistry (IHC) of anti-AGFG1 antibody

Immunohistochemistry of paraffin-embedded Human breast cancer using AGFG1 Polyclonal Antibody at dilution of 1:50
Rabbit Anti-AGFG1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2527227

Immunohistochemistry (IHC) of anti-AGFG1 antibody

Immunohistochemistry of paraffin-embedded Human colon cancer using AGFG1 Polyclonal Antibody at dilution of 1:50
Rabbit Anti-AGFG1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2527227

Other Notes

Small volumes of anti-AGFG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AGFG1 purchase

MBS2527227 is an antibody targeting AGFG1. Also known as AGFG1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AGFG1. It may not necessarily be applicable to this product.

NCBI GI #
206597509
NCBI GeneID
3267
NCBI Accession #
NP_001128661.1
UniProt Secondary Accession #
Q15277; Q4VAS0; Q4VAS1; Q4VAS3; Q53QT8; Q53R11; B3KUL1; E9PHX7
UniProt Related Accession #
P52594
GenBank Nucleotide #
NM_001135189.1
NCBI Official Full Name
arf-GAP domain and FG repeat-containing protein 1 isoform 4
NCBI Official Synonym Full Names
ArfGAP with FG repeats 1
NCBI Official Symbol
AGFG1
NCBI Official Synonym Symbols
HRB; RAB; RIP
UniProt Protein Name
Arf-GAP domain and FG repeat-containing protein 1
UniProt Synonym Protein Names
HIV-1 Rev-binding protein; Nucleoporin-like protein RIP; Rev-interacting protein; Rev/Rex activation domain-binding protein
Protein Family
Arf-GAP domain and FG repeat-containing protein
UniProt Gene Name
AGFG1
UniProt Synonym Gene Names
HRB; RAB; RIP
UniProt Entry Name
AGFG1_HUMAN
NCBI Protein Information
arf-GAP domain and FG repeat-containing protein 1; HIV-1 Rev binding protein; HIV-1 Rev-binding protein; Rab, Rev/Rex activation domain-binding protein; arf-GAP domain and FG repeats-containing protein 1; hRIP, Rev interacting protein; nucleoporin-like protein RIP; rev-interacting protein; rev/Rex activation domain-binding protein

UniProt Comments for AGFG1

RIP: Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element- containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. Interacts with EPS15R and EPS15. Interacts with FCHO1. Ubiquitously expressed. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear export; RNA-binding

Chromosomal Location of Human Ortholog: 2q36.3

Cellular Component: cell projection; cell soma; intracellular membrane-bound organelle; cytoplasmic membrane-bound vesicle; nuclear pore

Molecular Function: protein binding; DNA binding; zinc ion binding; RNA binding

Biological Process: acrosome formation; mRNA export from nucleus; multicellular organismal development; spermatid nuclear differentiation; intermediate filament organization; positive regulation of GTPase activity
Show more

Research Articles on AGFG1

1. Selenite caused CYLD upregulation via LEF1 and cIAP downregulation, both of which contribute to the degradation of ubiquitin chains on RIP1 and subsequent caspase-8 activation and colorectal tumor cell apoptosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AGFG1 antibody

 Reference Product  PubMed Publications
 EPS15 antibody  >4 publications with AGFG1 and EPS15
 RNF216 antibody  >1 publications with AGFG1 and RNF216
 VAMP7 antibody  >1 publications with AGFG1 and VAMP7

Pathways associated with anti-AGFG1 antibody

 Products by Pathway  Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram
 Influenza A Pathway antibodies  Influenza A Pathway Diagram

Diseases associated with anti-AGFG1 antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >72 publications with AGFG1 and Necrosis
 Inflammation Antibodies  >14 publications with AGFG1 and Inflammation
 Cell Transformation, Neoplastic Antibodies  >5 publications with AGFG1 and Cell Transformation, Neoplastic
 Liver Diseases Antibodies  >4 publications with AGFG1 and Liver Diseases
 Brain Diseases Antibodies  >3 publications with AGFG1 and Brain Diseases
 Liver Neoplasms Antibodies  >3 publications with AGFG1 and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >2 publications with AGFG1 and Neoplasm Metastasis
 Carcinoma, Hepatocellular Antibodies  >2 publications with AGFG1 and Carcinoma, Hepatocellular
 Infertility, Male Antibodies  >2 publications with AGFG1 and Infertility, Male
 Liver Neoplasms, Experimental Antibodies  >1 publications with AGFG1 and Liver Neoplasms, Experimental

Organs/Tissues associated with anti-AGFG1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >15 publications with AGFG1 and Lung
 Blood Antibodies  >14 publications with AGFG1 and Blood
 Liver Antibodies  >5 publications with AGFG1 and Liver
 Brain Antibodies  >5 publications with AGFG1 and Brain
 Kidney Antibodies  >4 publications with AGFG1 and Kidney
 Heart Antibodies  >4 publications with AGFG1 and Heart
 Vascular Antibodies  >3 publications with AGFG1 and Vascular
 Prostate Antibodies  >2 publications with AGFG1 and Prostate
 Bone Antibodies  >2 publications with AGFG1 and Bone
 Muscle Antibodies  >2 publications with AGFG1 and Muscle
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000