• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IGF2BP1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2528887

This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IGF2BP1, Polyclonal Antibody
Full Product Name
IGF2BP1 Polyclonal Antibody
Product Gene Name
anti-IGF2BP1 antibody
Product Synonym Names
IMP1, ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.5mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
48,598 Da
OMIM
608288
Immunogen
Synthetic peptide of human IGF2BP1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3

Product Categories/Family for anti-IGF2BP1 antibody

Epigenetics
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IGF2BP1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-IGF2BP1 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200

Western Blot (WB) of anti-IGF2BP1 antibody

Western Blot analysis of Hela cell using IGF2BP1 Polyclonal Antibody at dilution of 1:750
Rabbit Anti-IGF2BP1 Polyclonal Antibody – Cat# MBS2528887

Immunohistochemistry (IHC) of anti-IGF2BP1 antibody

Immunohistochemistry of paraffin-embedded Human liver cancer using IGF2BP1 Polyclonal Antibody at dilution of 1:40
Rabbit Anti-IGF2BP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2528887

Immunohistochemistry (IHC) of anti-IGF2BP1 antibody

Immunohistochemistry of paraffin-embedded Human lung cancer using IGF2BP1 Polyclonal Antibody at dilution of 1:40
Rabbit Anti-IGF2BP1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2528887

Other Notes

Small volumes of anti-IGF2BP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGF2BP1 purchase

MBS2528887 is an antibody targeting IGF2BP1. Also known as IGF2BP1 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IGF2BP1. It may not necessarily be applicable to this product.

NCBI GI #
56237027
NCBI GeneID
10642
NCBI Accession #
NP_006537.3
UniProt Secondary Accession #
C9JT33
UniProt Related Accession #
Q9NZI8
GenBank Nucleotide #
NM_006546.3
NCBI Official Full Name
insulin-like growth factor 2 mRNA-binding protein 1 isoform 1
NCBI Official Synonym Full Names
insulin-like growth factor 2 mRNA binding protein 1
NCBI Official Symbol
IGF2BP1
NCBI Official Synonym Symbols
IMP1; ZBP1; CRDBP; IMP-1; CRD-BP; VICKZ1
UniProt Protein Name
Insulin-like growth factor 2 mRNA-binding protein 1
UniProt Synonym Protein Names
Coding region determinant-binding protein; CRD-BP; IGF-II mRNA-binding protein 1; VICKZ family member 1; Zipcode-binding protein 1; ZBP-1
Protein Family
Insulin-like growth factor 2 mRNA-binding protein
UniProt Gene Name
IGF2BP1
UniProt Synonym Gene Names
CRDBP; VICKZ1; ZBP1; IGF2 mRNA-binding protein 1; IMP-1; IMP1; CRD-BP; ZBP-1
UniProt Entry Name
IF2B1_HUMAN
NCBI Protein Information
insulin-like growth factor 2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; IGF2 mRNA-binding protein 1; VICKZ family member 1; ZBP-1; coding region determinant-binding protein; zipcode-binding protein 1

UniProt Comments for IGF2BP1

IGF2BP1: a conserved trans-acting factor that can control translation of specific mRNAs in vivo. Contains four K homology (KH) domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the target mRNAs and repressing translation. Target mRNAs include those encoding beta-actin and insulin-like growth factor 2 (IGF2). Tyrosine phosphorylation apparently abolishes translational repression of actin expression by decreasing its binding beta-actin mRNA. May have a role in progression of ovarian cancer. Contains nuclear export signals within the RNA-binding KH2 and KH4 domains. Aberrant expression may interfere with c-myc regulation.

Protein type: RNA-binding; Translation

Chromosomal Location of Human Ortholog: 17q21.32

Cellular Component: growth cone; axon; stress granule; lamellipodium; perinuclear region of cytoplasm; cytoplasm; dendritic spine; nucleus; ribonucleoprotein complex; cytosol; filopodium

Molecular Function: mRNA binding; protein binding; mRNA 3'-UTR binding; nucleotide binding; translation regulator activity; mRNA 5'-UTR binding

Biological Process: mRNA transport; negative regulation of translation; gene expression; regulation of cytokine biosynthetic process
Show more

Research Articles on IGF2BP1

1. A 14;17 translocation resulting in an IGH-IGF2BP1 fusion is associated with B acute lymphoblastic leukemia.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IGF2BP1 antibody

 Reference Product  PubMed Publications
 IGF2 antibody  >11 publications with IGF2BP1 and IGF2
 MYC antibody  >6 publications with IGF2BP1 and MYC
 DHX9 antibody  >3 publications with IGF2BP1 and DHX9
 ACTB antibody  >2 publications with IGF2BP1 and ACTB
 YBX1 antibody  >2 publications with IGF2BP1 and YBX1
 CD44 antibody  >1 publications with IGF2BP1 and CD44
 SYNCRIP antibody  >1 publications with IGF2BP1 and SYNCRIP
 HNRNPU antibody  >1 publications with IGF2BP1 and HNRNPU
 CTNNB1 antibody  >1 publications with IGF2BP1 and CTNNB1

Pathways associated with anti-IGF2BP1 antibody

 Products by Pathway  Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Insulin-like Growth Factor-2 MRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) Bind RNA Pathway antibodies  Insulin-like Growth Factor-2 MRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) Bind RNA Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram

Diseases associated with anti-IGF2BP1 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >4 publications with IGF2BP1 and Liver Diseases
 Carcinoma Antibodies  >4 publications with IGF2BP1 and Carcinoma
 Hepatitis Antibodies  >4 publications with IGF2BP1 and Hepatitis
 Abnormalities, Multiple Antibodies  >2 publications with IGF2BP1 and Abnormalities, Multiple
 Birth Weight Antibodies  >1 publications with IGF2BP1 and Birth Weight
 Infertility, Female Antibodies  >1 publications with IGF2BP1 and Infertility, Female
 Necrosis Antibodies  >1 publications with IGF2BP1 and Necrosis

Organs/Tissues associated with anti-IGF2BP1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with IGF2BP1 and Liver
 Blood Antibodies  >4 publications with IGF2BP1 and Blood
 Brain Antibodies  >2 publications with IGF2BP1 and Brain
 Bone Antibodies  >2 publications with IGF2BP1 and Bone
 Lymph Antibodies  >1 publications with IGF2BP1 and Lymph
 Ovary Antibodies  >1 publications with IGF2BP1 and Ovary
 Lymph Node Antibodies  >1 publications with IGF2BP1 and Lymph Node
 Intestine Antibodies  >1 publications with IGF2BP1 and Intestine
 Muscle Antibodies  >1 publications with IGF2BP1 and Muscle
 Placenta Antibodies  >1 publications with IGF2BP1 and Placenta
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000