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CELSR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2529415

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CELSR2, Polyclonal Antibody
Full Product Name
CELSR2 Polyclonal Antibody
Product Gene Name
anti-CELSR2 antibody
Product Synonym Names
EGFL2; MEGF3; CDHF10; Flamingo1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Concentration
1.6mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Molecular Weight
317,453 Da
OMIM
604265
Immunogen
Synthetic peptide of human CELSR2
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CELSR2 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-CELSR2 antibody
IHC: 1:50-1:200

Immunohistochemistry (IHC) of anti-CELSR2 antibody

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using CELSR2 Polyclonal Antibody at dilution 1:50
Rabbit Anti-CELSR2 Polyclonal Antibody – Cat# MBS2529415

Immunohistochemistry (IHC) of anti-CELSR2 antibody

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CELSR2 Polyclonal Antibody at dilution 1:50
Rabbit Anti-CELSR2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2529415

Other Notes

Small volumes of anti-CELSR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CELSR2 purchase

MBS2529415 is an antibody targeting CELSR2. Also known as CELSR2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CELSR2. It may not necessarily be applicable to this product.

NCBI GI #
22095550
NCBI GeneID
1952
NCBI Accession #
Q9HCU4.1
UniProt Secondary Accession #
Q5T2Y7; Q92566
UniProt Related Accession #
Q9HCU4
NCBI Official Full Name
Cadherin EGF LAG seven-pass G-type receptor 2
NCBI Official Synonym Full Names
cadherin, EGF LAG seven-pass G-type receptor 2
NCBI Official Symbol
CELSR2
NCBI Official Synonym Symbols
EGFL2; MEGF3; CDHF10; Flamingo1
UniProt Protein Name
Cadherin EGF LAG seven-pass G-type receptor 2
UniProt Synonym Protein Names
Cadherin family member 10; Epidermal growth factor-like protein 2; EGF-like protein 2; Flamingo homolog 3; Multiple epidermal growth factor-like domains protein 3; Multiple EGF-like domains protein 3
Protein Family
Cadherin EGF LAG seven-pass G-type receptor
UniProt Gene Name
CELSR2
UniProt Synonym Gene Names
CDHF10; EGFL2; KIAA0279; MEGF3; EGF-like protein 2; Multiple EGF-like domains protein 3
UniProt Entry Name
CELR2_HUMAN
NCBI Protein Information
cadherin EGF LAG seven-pass G-type receptor 2; EGF-like protein 2; EGF-like-domain, multiple 2; cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); epidermal growth factor-like 2; epidermal growth factor-like protein 2; flamingo homolog 3; multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3

UniProt Comments for CELSR2

CELSR2: Receptor that may have an important role in cell/cell signaling during nervous system formation. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.

Protein type: Cell development/differentiation; Membrane protein, multi-pass; GPCR, family 2; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1p21

Cellular Component: cytoplasm; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cerebrospinal fluid secretion; regulation of cell-cell adhesion; regulation of protein localization; Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; ventricular system development; neural plate anterioposterior pattern formation; dendrite morphogenesis; neuron migration; cilium biogenesis; homophilic cell adhesion
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Research Articles on CELSR2

1. Observational study, meta-analysis, and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CELSR2 antibody

 Reference Product  PubMed Publications
 PSRC1 antibody  >27 publications with CELSR2 and PSRC1
 SORT1 antibody  >22 publications with CELSR2 and SORT1
 PCSK9 antibody  >7 publications with CELSR2 and PCSK9
 VANGL2 antibody  >7 publications with CELSR2 and VANGL2
 VANGL1 antibody  >6 publications with CELSR2 and VANGL1
 RYK antibody  >1 publications with CELSR2 and RYK

Pathways associated with anti-CELSR2 antibody

 Products by Pathway  Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram

Diseases associated with anti-CELSR2 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >21 publications with CELSR2 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >4 publications with CELSR2 and Nervous System Diseases
 Liver Diseases Antibodies  >2 publications with CELSR2 and Liver Diseases
 Congenital Abnormalities Antibodies  >1 publications with CELSR2 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >1 publications with CELSR2 and Disease Models, Animal
 Hypertension Antibodies  >1 publications with CELSR2 and Hypertension
 Hypertrophy Antibodies  >1 publications with CELSR2 and Hypertrophy
 Nervous System Malformations Antibodies  >1 publications with CELSR2 and Nervous System Malformations
 Neoplasms, Experimental Antibodies  >1 publications with CELSR2 and Neoplasms, Experimental
 Embryo Loss Antibodies  >1 publications with CELSR2 and Embryo Loss

Organs/Tissues associated with anti-CELSR2 antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >18 publications with CELSR2 and Heart
 Brain Antibodies  >18 publications with CELSR2 and Brain
 Vascular Antibodies  >6 publications with CELSR2 and Vascular
 Embryonic Tissue Antibodies  >5 publications with CELSR2 and Embryonic Tissue
 Lung Antibodies  >4 publications with CELSR2 and Lung
 Nerve Antibodies  >4 publications with CELSR2 and Nerve
 Liver Antibodies  >3 publications with CELSR2 and Liver
 Kidney Antibodies  >2 publications with CELSR2 and Kidney
 Eye Antibodies  >2 publications with CELSR2 and Eye
 Skin Antibodies  >2 publications with CELSR2 and Skin
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