Rabbit Anti-RAP1 Polyclonal Antibody – Cat# MBS2537267

Western Blot analysis of 293 cells using RAP1 Polyclonal Antibody at dilution of 1:500.

RAP1 Antibody – Rabbit Polyclonal

Name: RAP1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2537267
Price: 160 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2537267

MBS2537267 is an antibody targeting RAP1. Also known as RAP1 Polyclonal Antibody. Reactive in Human. Host: Rabbit. More details

$160 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RAP1, Polyclonal Antibody

Full Product Name

RAP1 Polyclonal Antibody

Product Gene Name

anti-RAP1 antibody

Product Synonym Names

TERF2IP; DRIP5; RAP1; PP8000; Telomeric repeat-binding factor 2-interacting protein 1; TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; Dopamine receptor-interacting protein 5; Repressor/activator protein 1 homol

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Purity/Purification

Antigen Affinity Purified

Concentration

1 mg/ml (lot specific)

Preparation and Storage

Store at -20 degree C. Avoid freeze / thaw cycles.

Molecular Weight

Calculated MW: 44
Observed MW: 55

OMIM

609700

Immunogen

Synthesized peptide derived from the Internal region of human RAP1.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-RAP1 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-RAP1 antibody

WB: 1:500-1:2000, ELISA: 1:5000-1:20000

Other Notes

Small volumes of anti-RAP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RAP1. It may not necessarily be applicable to this product.

NCBI GI #

77176717

NCBI Accession #

ABA64473.1

UniProt Secondary Accession #

Q3HKR2; Q3HKR3; Q53FG0; B4DZM7

NCBI Official Full Name

RAP1

UniProt Protein Name

Rab5 GDP/GTP exchange factor

UniProt Synonym Protein Names

RAP1; Rabaptin-5-associated exchange factor for Rab5; Rabex-5

Protein Family

DNA-binding protein

UniProt Gene Name

RABGEF1

UniProt Synonym Gene Names

RABEX5

UniProt Entry Name

RABX5_HUMAN

UniProt Comments for RAP1

RABGEF1: Rab effector protein acting as linker between gamma- adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. Interacts with RGS14; the interaction is GTP-dependent. Heterodimer with RABEP1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Interacts with RAB21, and with 100-fold lower affinity also with RAB22. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2. Interacts with ubiquitinated EGFR. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; GAPs, Rab

Chromosomal Location of Human Ortholog: 7q11.21

Cellular Component: early endosome; recycling endosome; vesicle

Molecular Function: DNA binding; protein binding; Rab GTPase binding; Rab guanyl-nucleotide exchange factor activity; zinc ion binding

Biological Process: endocytosis; negative regulation of inflammatory response; negative regulation of leukocyte migration; negative regulation of mast cell degranulation; negative regulation of protein amino acid phosphorylation; negative regulation of Ras protein signal transduction; negative regulation of receptor-mediated endocytosis; positive regulation of GTPase activity; protein targeting to membrane; protein ubiquitination

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.