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TrxR2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2539499

MBS2539499 is an antibody targeting TrxR2. Also known as TrxR2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TrxR2, Polyclonal Antibody
Full Product Name
TrxR2 Polyclonal Antibody
Product Gene Name
Product Synonym Names
TXNRD2; KIAA1652; TRXR2; Thioredoxin reductase 2; mitochondrial; Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Concentration
1 mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Molecular Weight
Calculated MW: 56
Observed MW: 56
OMIM
606448
Immunogen
Synthesized peptide derived from the C-terminal region of human TrxR2.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TrxR2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-TrxR2 antibody
WB: 1:500-1:2000, IHC: 1:50-1:200, ELISA: 1:5000-1:20000

Western Blot (WB) of anti-TrxR2 antibody

Western Blot analysis of Rat Muscle cells using TrxR2 Polyclonal Antibody at dilution of 1:20000.
Rabbit Anti-TrxR2 Polyclonal Antibody – Cat# MBS2539499

Western Blot (WB) of anti-TrxR2 antibody

Western Blot analysis of HT29 cells using TrxR2 Polyclonal Antibody at dilution of 1:20000.
Rabbit Anti-TrxR2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS2539499

Other Notes

Small volumes of anti-TrxR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TrxR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thioredoxin reductase 2, mitochondrial isoform 2
NCBI Official Synonym Full Names
thioredoxin reductase 2
NCBI Official Symbol
TXNRD2
NCBI Official Synonym Symbols
TR; TR3; SELZ; TRXR2; TR-BETA
UniProt Protein Name
Thioredoxin reductase 2, mitochondrial
UniProt Synonym Protein Names
Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3
UniProt Gene Name
TXNRD2
UniProt Synonym Gene Names
KIAA1652; TRXR2; SelZ
UniProt Entry Name
TRXR2_HUMAN
NCBI Protein Information
thioredoxin reductase 2, mitochondrial

NCBI Summary for TrxR2

This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013]
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UniProt Comments for TrxR2

TXNRD2: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.8.1.9; Nucleotide Metabolism - pyrimidine; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: FAD binding; protein binding; thioredoxin-disulfide reductase activity

Biological Process: cell redox homeostasis; response to oxygen radical; response to reactive oxygen species
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TrxR2 antibody

 Reference Product  PubMed Publications
 TXN2 antibody  >10 publications with TrxR2 and TXN2
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