Rat Anti-CD103 Monoclonal Antibody – Cat# MBS2558540

C57BL/6 murine splenocytes are stained with Anti-Mouse CD103 Monoclonal Antibody (AF488 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.

CD103 Antibody – Rat Monoclonal

Name: CD103 Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2558540
Price: 160 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2558540

CD103 is a type I transmembrane glycoprotein known as alphaE integrin or Integrin alphaIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina… More details

$160 / 0.025 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD103, Monoclonal Antibody

Full Product Name

Anti-Mouse CD103 Monoclonal Antibody (AF488 Conjugated) [M290]

Product Gene Name

anti-CD103 antibody

Product Synonym Gene Name

Mouse CD103

Product Synonym Names

Integrin alpha-E; Itgae; Integrin alpha M290; CD103

Clonality

Monoclonal

Isotype

IgG2a, kappa

Clone Number

M290

Host

Rat

Species Reactivity

Mouse

Form/Format

PBS with 0.05% Proclin300, 1% BSA

Concentration

0.5 mg/mL (lot specific)

Preparation and Storage

Store at 2-8 degree C and protect from prolonged exposure to light. Do not freeze.

Matching Pairs

Antibody: CD103 (MBS2558540)
Isotype Control: IgG2a Clone #2A3 (MBS2557863)

3D Structure

ModBase 3D Structure for Q60677

Conjugation

AF488

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CD103 antibody

Flow Cytometry (FC/FACS)

Application Notes for anti-CD103 antibody

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <= 2 ug per 10⁶ cells in 100 ul volume or 100 ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Other Notes

Small volumes of anti-CD103 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD103 purchase

MBS2558540 is an antibody targeting CD103. Also known as Anti-Mouse CD103 Monoclonal Antibody (AF488 Conjugated) [M290]. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CD103. It may not necessarily be applicable to this product.

NCBI GI #

226823202

NCBI GeneID

16407

NCBI Accession #

NP_032425.2

UniProt Primary Accession #

Q60677

UniProt Related Accession #

Q60677

GenBank Nucleotide #

NP_032425.2

NCBI Official Full Name

integrin alpha-E isoform 1

NCBI Official Synonym Full Names

integrin alpha E, epithelial-associated

NCBI Official Symbol

Itgae

NCBI Official Synonym Symbols

CD103; aM290; alpha-E1; A530055J10; alpha-M290

UniProt Protein Name

Integrin alpha-E

UniProt Synonym Protein Names

Integrin alpha M290; CD_antigen: CD103Cleaved into the following 2 chains:Integrin alpha-E light chain; Integrin alpha-E heavy chain

Protein Family

Integrin

UniProt Gene Name

Itgae

UniProt Entry Name

ITAE_MOUSE

NCBI Protein Information

integrin alpha-E

UniProt Comments for CD103

ITGAE: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Belongs to the integrin alpha chain family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Cellular Component: membrane; integral to membrane; integrin complex; external side of plasma membrane

Molecular Function: metal ion binding

Biological Process: integrin-mediated signaling pathway; cell adhesion

Research Articles on CD103

1. CD103(+) cDCs counterregulated CD11b(+) cDC-mediated Th1 activation directly by producing the immune-suppressive cytokine IL-10.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD103 antibody

Products by Pathway	Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Integrin Cell Surface Interactions Pathway antibodies	Integrin Cell Surface Interactions Pathway Diagram
Integrin-mediated Cell Adhesion Pathway antibodies	Integrin-mediated Cell Adhesion Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram

Diseases associated with anti-CD103 antibody

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>3 publications with CD103 and Lung Diseases
Inflammation Antibodies	>3 publications with CD103 and Inflammation
Skin Diseases Antibodies	>2 publications with CD103 and Skin Diseases
Adenocarcinoma Antibodies	>1 publications with CD103 and Adenocarcinoma
Lung Neoplasms Antibodies	>1 publications with CD103 and Lung Neoplasms
Lymphoma Antibodies	>1 publications with CD103 and Lymphoma
Heart Diseases Antibodies	>1 publications with CD103 and Heart Diseases
Pneumonia Antibodies	>1 publications with CD103 and Pneumonia
Neoplasms, Experimental Antibodies	>1 publications with CD103 and Neoplasms, Experimental
Fibrosis Antibodies	>1 publications with CD103 and Fibrosis

Organs/Tissues associated with anti-CD103 antibody

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>2 publications with CD103 and Skin
Embryonic Tissue Antibodies	>1 publications with CD103 and Embryonic Tissue
Testis Antibodies	>1 publications with CD103 and Testis