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GTF2A2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2560771

Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
GTF2A2, Polyclonal Antibody
Full Product Name
GTF2A2 Polyclonal Antibody
Product Gene Name
anti-GTF2A2 antibody
Product Synonym Names
General transcription factor IIA; General transcription factor IIA subunit 2; General transcription factor IIA, 2 (12kD subunit); General transcription factor IIA, 2, 12kDa; Gtf2a2; HsT18745; T2AG; TF2A2; TFIIA 12; TFIIA; TFIIA gamma; TFIIA p12 subunit; TFIIA-12; TFIIA-gamma; TFIIA12; TFIIAS; Transcription initiation factor IIA gamma chain; Transcription initiation factor IIA subunit 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.54mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
OMIM
600519
3D Structure
ModBase 3D Structure for P52657
Immunogen
Fusion protein of human GTF2A2
Conjugation
Unconjugated

Product Categories/Family for anti-GTF2A2 antibody

Epigenetics and Nuclear Signaling
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-GTF2A2 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-GTF2A2 antibody
IHC: 1:30-1:150
ELISA: 1:5000-1:10000

Immunohistochemistry (IHC) of anti-GTF2A2 antibody

Immunohistochemistry of paraffin-embedded Human liver cancer tissue using GTF2A2 Polyclonal Antibody at dilution of 1:30(×200)
Rabbit Anti-GTF2A2 Polyclonal Antibody – Cat# MBS2560771

Immunohistochemistry (IHC) of anti-GTF2A2 antibody

Immunohistochemistry of paraffin-embedded Human tonsil tissue using GTF2A2 Polyclonal Antibody at dilution of 1:30(×200)
Rabbit Anti-GTF2A2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2560771

Other Notes

Small volumes of anti-GTF2A2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GTF2A2 purchase

MBS2560771 is an antibody targeting GTF2A2. Also known as GTF2A2 Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GTF2A2. It may not necessarily be applicable to this product.

NCBI GI #
49457380
NCBI GeneID
2958
NCBI Accession #
CAG46989.1
NCBI Related Accession #
BC000287
UniProt Primary Accession #
P52657
UniProt Related Accession #
P52657
NCBI Official Full Name
GTF2A2, partial
NCBI Official Synonym Full Names
general transcription factor IIA subunit 2
NCBI Official Symbol
GTF2A2
NCBI Official Synonym Symbols
TF2A2; TFIIA; T18745; TFIIAS; HsT18745; TFIIA-12; TFIIA-gamma
UniProt Protein Name
Transcription initiation factor IIA subunit 2
UniProt Synonym Protein Names
General transcription factor IIA subunit 2; TFIIA p12 subunit; TFIIA-12; TFIIAS; Transcription initiation factor IIA gamma chain; TFIIA-gamma
UniProt Gene Name
GTF2A2
UniProt Synonym Gene Names
TF2A2; TFIIA-12; TFIIAS; TFIIA-gamma
UniProt Entry Name
T2AG_HUMAN
NCBI Protein Information
transcription initiation factor IIA subunit 2

UniProt Comments for GTF2A2

GTF2A2: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. Belongs to the TFIIA subunit 2 family.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: cell junction; nucleoplasm; transcription factor TFIIA complex

Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity; TATA-binding protein binding; transcription coactivator activity; transcription factor binding

Biological Process: positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter; transcriptional preinitiation complex assembly; viral reproduction
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Research Articles on GTF2A2

1. Data suggest that many TATA-box-containing promoters contain a TFIIA recognition element (IIARE) that activates transcription by increasing the recruitment of RNA polymerase II, TFIIA (TF2A1/TF2A2 subunits), TAF4, and P300. (TAF4 = TATA box binding protein (TBP)-associated factor, RNA polymerase II, C1; P300 = E1A binding protein p300)
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-GTF2A2 antibody

 Products by Pathway  Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Basal Transcription Factors Pathway antibodies  Basal Transcription Factors Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Eukaryotic Transcription Initiation Pathway antibodies  Eukaryotic Transcription Initiation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 HIV Infection Pathway antibodies  HIV Infection Pathway Diagram
 HIV Life Cycle Pathway antibodies  HIV Life Cycle Pathway Diagram
 HIV Transcription Initiation Pathway antibodies  HIV Transcription Initiation Pathway Diagram
 Infectious Disease Pathway antibodies  Infectious Disease Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram

Organs/Tissues associated with anti-GTF2A2 antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >1 publications with GTF2A2 and Testis
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