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TRMT12 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2560934

Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRMT12, Polyclonal Antibody
Full Product Name
TRMT12 Polyclonal Antibody
Product Gene Name
Product Synonym Names
Alpha amino alpha carboxypropyl transferase TYW2; FLJ20772; Homolog of yeast tRNA methyltransferase; Radical S-adenosyl methionine and flavodoxin domain-containing protein 2; TRM 12; TRM12; TRMT 12; TRMT12; TRNA methyltransferase 12; TRNA methyltransferase 12 homolog; TRNA wybutosine-synthesizing protein 2 homolog; TRNA-yW-synthesizing protein 2; TYW2; TYW2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Rat
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
1.44mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
OMIM
611244
3D Structure
ModBase 3D Structure for Q53H54
Immunogen
Fusion protein of human TRMT12
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TRMT12 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-TRMT12 antibody
IHC: 1:50-1:300
ELISA: 1:5000-1:10000

Immunohistochemistry (IHC) of anti-TRMT12 antibody

Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TRMT12 Polyclonal Antibody at dilution of 1:80(×200)
Rabbit Anti-TRMT12 Polyclonal Antibody – Cat# MBS2560934

Immunohistochemistry (IHC) of anti-TRMT12 antibody

Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TRMT12 Polyclonal Antibody at dilution of 1:80(×200)
Rabbit Anti-TRMT12 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2560934

Other Notes

Small volumes of anti-TRMT12 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRMT12 purchase

MBS2560934 is an antibody targeting TRMT12. Also known as TRMT12 Polyclonal Antibody. Reactive in Human, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TRMT12. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tRNA wybutosine-synthesizing protein 2 homolog
NCBI Official Synonym Full Names
tRNA methyltransferase 12 homolog
NCBI Official Symbol
TRMT12
NCBI Official Synonym Symbols
TYW2; TRM12
UniProt Protein Name
tRNA wybutosine-synthesizing protein 2 homolog
UniProt Synonym Protein Names
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase
UniProt Gene Name
TRMT12
UniProt Synonym Gene Names
TRM12; TYW2; tRNA-yW-synthesizing protein 2
UniProt Entry Name
TYW2_HUMAN
NCBI Protein Information
tRNA wybutosine-synthesizing protein 2 homolog

UniProt Comments for TRMT12

TRMT12: Probable S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Belongs to the TRM5 / TYW2 family.

Protein type: Methyltransferase; EC 2.5.1.114

Chromosomal Location of Human Ortholog: 8q24.13

Molecular Function: transferase activity

Biological Process: tRNA processing
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-TRMT12 antibody

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