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2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- diphosphate (MANT-dGDP)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS256147

MANT-dGDP is an analogue of the parent nucleotide 2'-deoxyguanosine-5'-O-diphosphate (dGDP) in which the 3'- hydroxy group is esterified by the fluorescent methylisatoic acid. More details

$750 / 5 umol +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- diphosphate (MANT-dGDP), Biochemical
Full Product Name
2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- diphosphate (MANT-dGDP)
Purity/Purification
Typical purity is better than 95% (HPLC / UV / 252 nm) at time of quality control and packing. However, actual purity depends on storage and transport conditions. The product is not sterile and has not been tested for endotoxins.
Preparation and Storage
MANT-dGDP is most stable when stored as aqueous solution in the freezer (-20 degree Celsius necessary, -80 degree C recommended), however, at ambient temperature the compound slowly starts to decompose. In order to maintain its original high quality it is recommended to protect the product from light and to allow thawing only before using the product. If you will not use up the vial with one application, please aliquot the contents of the vial in order to avoid repeated freeze/thaw cycles for the rest. When making such aliquots be sure to operate quickly and to freeze the vial again as soon as possible.
Shipping: Ships with Dry Ice
Molecular Weight
560.4 (Free acid)
Unit Equivalent
5 umol is approximately equals to 2.8 mg
CAS No.
127383-33-9
Properties
Fluorescent analogue with lambdaexc 350 nm and lambdaem 442 nm, useful for research into dGDP-dependent receptor proteins. The MANT fluorophore has a certain sensitivity for its environment and can change its spectral properties upon binding.
Specification
Aqueous solution of the sodium salt (10 mM, pH 7.6). Other salt forms of MANT-dGDP are available upon request. Micromolar quantities are determined by UV at 355 nm. When opening the tube please make sure that no liquid is lost within the cap. A short spin-down in a bench centrifuge is recommended before use.
Formula
C18H22N6O11P2 Free acid)
Toxicity and Safety
Since nucleoside diphosphates have multiple tasks in every organism, it is very likely that GDP analogues will interfere with many cell regulation processes in vivo. However, due to the rather small quantities to work with, no health hazards have been reported. Never heless please keep in mind, that the in vivo properties of this compound are not sufficiently characterized up to now. Avoid skin contact or ingestion and allow only trained personnel to handle the product.

Our products are designed, developed and sold for research purposes only! They are intended for in vitro and nonhuman in vivo laboratory applications. Any other use requires approval of health authorities.
UV
Lambdamax252nm / & 22600 / pH8

Other Notes

Small volumes of 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- diphosphate (MANT-dGDP) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS256147 is a biochemical targeting 2'- Deoxy- 3'- O- (N'- methylanthraniloyl)guanosine- 5'- O- diphosphate (MANT-dGDP).
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