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PRPF8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2561633

Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains… More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRPF8, Polyclonal Antibody
Full Product Name
PRPF8 Polyclonal Antibody
Product Gene Name
Product Synonym Names
220 kDa U5 snRNP specific protein; 220 kDa U5 snRNP-specific protein; Apoptosis regulated protein 1; Apoptosis regulated protein 2; HPRP8; P220; Pre mRNA processing factor 8; Pre mRNA-processing factor 8, S. cerevisiae, homolog of; Pre-mRNA-processing-splicing factor 8; Precursor mRNA processing protein; PRP8; PRP8 homolog; PRP8 pre mRNA processing factor 8 homolog; PRP8; PRPC8; Prpf8; Retinitis pigmentosa 13 (autosomal dominant); RP13; SNRNP220; Splicing factor Prp8; U5 snRNP specific protein; U5 snRNP specific protein (220 kD), ortholog of S. cerevisiae Prp8p
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
0.6mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
274 kDa
OMIM
600059
3D Structure
ModBase 3D Structure for Q6P2Q9
Immunogen
Synthetic peptide of human PRPF8
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-PRPF8 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PRPF8 antibody
WB: 1:500-1:2000
ELISA: 1:5000-1:10000

Western Blot (WB) of anti-PRPF8 antibody

Western blot analysis of 293T K562 Raji Hela and NIH/3T3 cell lysates using PRPF8 Polyclonal Antibody at dilution of 1:600
Rabbit Anti-PRPF8 Polyclonal Antibody – Cat# MBS2561633

Other Notes

Small volumes of anti-PRPF8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRPF8 purchase

MBS2561633 is an antibody targeting PRPF8. Also known as PRPF8 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PRPF8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Pre-mRNA-processing-splicing factor 8
NCBI Official Synonym Full Names
pre-mRNA processing factor 8
NCBI Official Symbol
PRPF8
NCBI Official Synonym Symbols
PRP8; RP13; HPRP8; PRPC8; SNRNP220
UniProt Protein Name
Pre-mRNA-processing-splicing factor 8
UniProt Synonym Protein Names
220 kDa U5 snRNP-specific protein; PRP8 homolog; Splicing factor Prp8; p220
UniProt Gene Name
PRPF8
UniProt Synonym Gene Names
PRPC8
NCBI Protein Information
pre-mRNA-processing-splicing factor 8

UniProt Comments for PRPF8

Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PRPF8 antibody

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