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2'- Deoxyguanosine- 3', 5'- cyclic monophosphate (2'-dcGMP)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS256174

2'-dcGMP is an analogue of the natural signal molecule cyclic GMP in whichthe 2'-hydroxy group in the ribose moiety is lacking. More details

$510 / 10 umol +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
2'- Deoxyguanosine- 3', 5'- cyclic monophosphate (2'-dcGMP), Biochemical
Full Product Name
2'- Deoxyguanosine- 3', 5'- cyclic monophosphate (2'-dcGMP)
Purity/Purification
Typical analysis is better than 98% (HPLC /UV/ 252 nm). The product is not sterile and has not been tested for endotoxins.
Specificity
Lyophilized or crystallized sodium salt. The free acid or other saltforms of 2'-dcGMP are available upon request. Please keep in mind that equal concentrations of the compound may look different in volumedue to sensitivity of the lyophilized form to humidity. The compound can even contract to small volume droplets. Normally the product is located in the conical bottom of the tube. Micromolar quantities are determined by UV at λ max.
Preparation and Storage
2'-dcGMP is chemically stable under conditions of biological systems and media. Nevertheless, we recommend that the compound should be stored in the freezer, for longer storage periods preferably in freeze-dried form.
Molecular Weight
351.2
Formula
C10H11N5O6P.Na
UV
λmax 252nm / ε 13500 / pH 7
Properties
Due to its lacking 2'-hydroxy group 2'-dcGMP can be useful for cGMP receptor mapping studies. Receptor proteins which need e.g. hydrogen bonds to recognize cyclic GMP at the 2' ribose part, will show considerably reduced binding affinity. 2'-dcGMP is, for example, an rather inactive control at cGMP-dependent protein kinases, for which an intact 2'-OH group is essentially required.
Solubility
2'-dcGMP is readily soluble in water or buffers. Please rinse tube walls carefully and preferably use ultrasonic or vortex to achieve total and uniform mixing. When opening the tube please make sure that no substance is lost within the cap.

Testing Data of 2'- Deoxyguanosine- 3', 5'- cyclic monophosphate (2'-dcGMP) biochemical

2'- Deoxyguanosine- 3', 5'- Cyclic Monophosphate (2'-Dcgmp) Biochemical – Cat# MBS256174

Other Notes

Small volumes of 2'- Deoxyguanosine- 3', 5'- cyclic monophosphate (2'-dcGMP) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 2'- Deoxyguanosine- 3', 5'- cyclic monophosphate (2'-dcGMP) purchase

MBS256174 is a biochemical targeting 2'- Deoxyguanosine- 3', 5'- cyclic monophosphate (2'-dcGMP).
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