Rabbit Anti-PDXK Polyclonal Antibody – Cat# MBS2563042

Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using PDXK Polyclonal Antibody at dilution of 1:75(×200)

PDXK Antibody – Rabbit Polyclonal

Name: PDXK Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2563042
Price: 160 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2563042

The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer.… More details

$160 / 0.02 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PDXK, Polyclonal Antibody

Full Product Name

PDXK Polyclonal Antibody

Product Gene Name

anti-PDXK antibody

Product Synonym Names

pdxK; PDXK; PKH; PNK; Pyridoxal kinase; Pyridoxamine kinase; Pyridoxine kinase; Pyridoxine kinase;; Vitamin B6 kinase

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Form/Format

PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purity/Purification

Antigen Affinity Purification

Concentration

1.32mg/mL (lot specific)

Preparation and Storage

Store at -20 degree C. Avoid freeze/thaw cycles.

OMIM

179020

3D Structure

ModBase 3D Structure for O00764

Immunogen

Fusion protein of human PDXK

Conjugation

Unconjugated

Product Categories/Family for anti-PDXK antibody

Cancer; Cell Biology; Metabolism; Signal transduction

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-PDXK antibody

Immunohistochemistry (IHC), ELISA (EIA)

Application Notes for anti-PDXK antibody

IHC: 1:50-1:200
ELISA: 1:5000-1:10000

Other Notes

Small volumes of anti-PDXK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PDXK purchase

MBS2563042 is an antibody targeting PDXK. Also known as PDXK Polyclonal Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PDXK. It may not necessarily be applicable to this product.

NCBI GI #

13543317

NCBI GeneID

8566

NCBI Accession #

AAH05825.1

NCBI Related Accession #

BC000123

UniProt Primary Accession #

O00764

UniProt Related Accession #

O00764

NCBI Official Full Name

PDXK protein

NCBI Official Synonym Full Names

pyridoxal kinase

NCBI Official Symbol

PDXK

NCBI Official Synonym Symbols

PKH; PNK; HMSN6C; PRED79; C21orf97; HEL-S-1a; C21orf124

UniProt Protein Name

Pyridoxal kinase

UniProt Synonym Protein Names

Pyridoxine kinase

Protein Family

Putative pyridoxine kinase

UniProt Gene Name

PDXK

UniProt Synonym Gene Names

C21orf124; C21orf97; PKH; PNK

UniProt Entry Name

PDXK_HUMAN

NCBI Protein Information

pyridoxal kinase

UniProt Comments for PDXK

PDXK: Required for synthesis of pyridoxal-5-phosphate from vitamin B6. Belongs to the pyridoxine kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.1.35; Cofactor and Vitamin Metabolism - vitamin B6; Kinase, other

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus

Molecular Function: potassium ion binding; sodium ion binding; protein homodimerization activity; zinc ion binding; pyridoxal kinase activity; magnesium ion binding; lithium ion binding; ATP binding; pyridoxal phosphate binding

Biological Process: cell proliferation; vitamin metabolic process; vitamin B6 metabolic process; pyridoxal 5'-phosphate salvage; phosphorylation; water-soluble vitamin metabolic process; pyridoxal phosphate biosynthetic process

Research Articles on PDXK

1. The affected pyridoxine metabolism is discussed as an inborn genetic trait in epilepsy in general, rather than a specific sign of pyridoxine-dependent epilepsy solely.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-PDXK antibody

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Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram
Vitamin B6 Metabolism Pathway antibodies	Vitamin B6 Metabolism Pathway Diagram
Vitamin B6 Metabolism Pathway antibodies	Vitamin B6 Metabolism Pathway Diagram
Vitamins B6 Activation To Pyridoxal Phosphate Pathway antibodies	Vitamins B6 Activation To Pyridoxal Phosphate Pathway Diagram