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8- Bromo- 7- deaza- cyclic adenosine diphosphate ribose (8-Br-7-CH-cADPR)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS256317

Description: 8-Br-7-CH-cADPR is an analogue of the second messenger cyclic adenosine diphosphate ribose (cADPR, CAT No. MBS256425) in which the hydrogen in position 8 of the heterocyclic nucleobase is replaced by bromine. In addition, the nitrogen atom in… More details

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Product Overview

Online Datasheet in PDF
Product Name
8- Bromo- 7- deaza- cyclic adenosine diphosphate ribose (8-Br-7-CH-cADPR), Biochemical
Full Product Name
8- Bromo- 7- deaza- cyclic adenosine diphosphate ribose (8-Br-7-CH-cADPR)
Purity/Purification
Typical analysis is better than 97% (HPLC / UV / 277 nm). The product is not sterile and has not been tested for endotoxins.
Specificity
Lyophilized or crystallized sodium salt. Other salt forms are available upon request. Equal concentrations of 8-Br-7-CH-cADPR can appear very different in volume due to sensitivity of the lyophilized form to humidity. The compound can even contract to small volume droplets. Normally the product is located in the conical bottom of the tube. Micromolar quantities are determined by UV at λmax.
Preparation and Storage
Ships on Dry Ice.
8-Br-7-CH-cADPR has limited stability at ambient temperature. Therefore, we recommend that the compound should be stored in the freezer (-20 degrees C necessary, - 80 degrees C recommended), for longer storage periods preferably in freeze-dried form.
Molecular Weight
619.2 (free acid)
CAS No.
189876-06-0
UV
λmax 277 nm / ε 10850 / pH 7
Properties
8-Br-7-CH-cADPR is a membrane-permeant and hydrolysis-resistant antagonist of the second messenger cADPR.
Formula
C16H21BrN4O13P2 (free acid)
Solubility
8-Br-7-CH-cADPR is easily soluble in water (> 50 mM). Please rinse tube walls carefully and preferably use ultrasonic or vortex to achieve total and uniform mixing. When opening the tube please make sure that no substance is lost within the cap.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.

Structure of 8- Bromo- 7- deaza- cyclic adenosine diphosphate ribose (8-Br-7-CH-cADPR) biochemical

8- Bromo- 7- Deaza- Cyclic Adenosine Diphosphate Ribose (8-Br-7-Ch-Cadpr) Biochemical – Cat# MBS256317

Other Notes

Small volumes of 8- Bromo- 7- deaza- cyclic adenosine diphosphate ribose (8-Br-7-CH-cADPR) biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 8- Bromo- 7- deaza- cyclic adenosine diphosphate ribose (8-Br-7-CH-cADPR) purchase

MBS256317 is a biochemical targeting 8- Bromo- 7- deaza- cyclic adenosine diphosphate ribose (8-Br-7-CH-cADPR).
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